6-Cyclopropyl-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(trifluoromethyl)nicotinonitrile CAS 625377-48-2
| CAS No. | 625377-48-2 |
| Molecular Formula | C19H15F3N2O2S |
| Molecular Weight | 392.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Cyclopropyl-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(trifluoromethyl)nicotinonitrile (C19H15F3N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 6-Cyclopropyl-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625377-48-2), a certified reference material (molecular formula C19H15F3N2O2S, MW 392.39 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H15F3N2O2S |
| Molecular Weight | 392.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Cyclopropyl Standards
- 6-Cyclopropyl-2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 625377-47-1)
- Ethyl 2-(3-cyclopropyl-6-(1-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1173047-60-3)
- 1-Cyclopropyl-7-(3-((ethylamino)methyl)pyrrolidin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 99734-97-1)
- 3-Cyclopropyl-1,6-bis(4-fluorophenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011396-68-1)
- Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-16-5)
- 5-(N-Cyclopropyl-N-(furan-2-ylmethyl)sulfamoyl)-N-(thiazol-2-yl)furan-2-carboxamide (CAS 1172704-71-0)
- 2-(3-Cyclopropyl-6-(2-methoxyphenyl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-16-1)
- 2-(3-Cyclopropyl-6-(3-methoxyphenyl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-18-3)
Recommended Standards
- 6-Benzyl-2-(3-nitrobenzylidene)-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 463364-65-0)
- 4-((2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)-N-(thiophen-2-ylmethyl)benzamide (CAS 339025-35-3)
- 9-(((Trifluoromethyl)sulfonyl)oxy)-6,7-dihydro-5H-benzo[7]annulen-2-yl pivalate (CAS 2114341-29-4)
- 3-(1-Pyrrolylmethyl)pyridine (CAS 80866-95-1)
- 5-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-methoxypyridine (CAS 5059-34-7)
- Methyl 3-acetyl-1H-indole-5-carboxylate (CAS 106896-59-7)
- Ethyl [(2,4-dinitrophenyl)amino]acetate (CAS 33414-81-2)
- Ethyl 7-chloro-1-cyclopropyl-6-fluoro-5-methyl-4-oxo-1,2,3,4-tetrahydro-1,8-naphthyridine-3-carboxylate (CAS 125290-82-6)
- 4-Oxo-4,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carbaldehyde (CAS 90490-57-6)
- 2,2,6,6-Tetramethylmorpholine hcl (CAS 167947-93-5)
- 2-(difluoromethyl)-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-3-carboxylic acid dihydrochloride (CAS 2059975-76-5)
- 2-(Methylamino)butanamide (CAS 1218229-30-1)
- 7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-amine (CAS 1189852-05-8)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com