N-(2-chlorobenzyl)-2-((6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide CAS 625377-95-9
| CAS No. | 625377-95-9 |
| Molecular Formula | C22H14Cl2F3N3OS |
| Molecular Weight | 496.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies N-(2-chlorobenzyl)-2-((6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 625377-95-9), a certified reference material (molecular formula C22H14Cl2F3N3OS, MW 496.33 g/mol) for analytical method development and quality control.
The molecular framework of N-(2-chlorobenzyl)-2-((6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (C22H14Cl2F3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H14Cl2F3N3OS |
| Molecular Weight | 496.33 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- Ethyl 2-(2-((2-chlorobenzyl)sulfonyl)-4,5-diphenyl-1H-imidazol-1-yl)acetate (CAS 339277-76-8)
- N-(4-chlorobenzyl)-N-(4-nitrophenyl)-2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332158-17-5)
- 5-((3-Chlorobenzyl)thio)-3-(cyclohexylmethyl)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024017-13-7)
- 5-((4-Chlorobenzyl)thio)-3-(cyclohexylmethyl)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024018-78-7)
- 4-[(4-Chlorobenzyl)oxy]-3,5-diiodobenzaldehyde (CAS 384857-14-1)
- 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-((2,4,6-trimethylbenzyl)thio)quinazolin-4(3H)-imine (CAS 860610-65-7)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-((2,5-dichlorophenyl)sulfonyl)-1H-pyrazole (CAS 477713-43-2)
- 3-Benzyl-5-((2-chlorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024594-44-2)
Recommended Standards
- 4-[(3,4-Dichlorobenzenesulfonyl)methyl]-1-[3-(trifluoromethyl)benzoyl]piperidin-4-ol (CAS 866019-58-1)
- 2-(2-((4-Bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide (CAS 1462267-08-8)
- Crizotinib Impurity 44 (CAS CATO-C4X-102544)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromo-2-methoxyphenyl)propanoic acid (CAS 220497-51-8)
- 4-Aminoacetophenone oxime (CAS 38063-81-9)
- Methyl 5-(bromomethyl)pyrimidine-2-carboxylate (CAS 76196-68-4)
- tert-butyl N-(5-methylpyrazin-2-yl)carbamate (CAS 369638-68-6)
- Dimethyl(4-(trifluoromethyl)phenyl)phosphine oxide (CAS 1333230-26-4)
- 5-Bromobenzofurazan 1-oxide (CAS 36387-84-5)
- 4,4-Dimethoxy-1-(thiophen-2-yl)butane-1,3-dione (CAS 1341946-92-6)
- Benzyl 1,2-oxazepane-2-carboxylate (CAS 1217295-83-4)
- 2-((3-Fluorobenzyl)sulfonyl)-1-methyl-4,5-diphenyl-1H-imidazole (CAS 338957-03-2)
- 1-Phenyl-3-piperidino-1,2-propanedione 2-[N-(2,4-dichlorophenyl)hydrazone] (CAS 866136-15-4)
- Semaglutide (CAS 910463-68-2)
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