4-Bromo-2-fluoroacetophenone, 97% CAS 625446-22-2
| CAS No. | 625446-22-2 |
| Molecular Formula | C8H6BrFO |
| Molecular Weight | 217.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-2-fluoroacetophenone, 97% is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Bromo-2-fluoroacetophenone, 97% (CAS 625446-22-2), a certified reference material (molecular formula C8H6BrFO, MW 217.04 g/mol) for analytical method development and quality control.
Structurally, 4-Bromo-2-fluoroacetophenone, 97% (C8H6BrFO) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 217.04 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2-fluoroacetophenone, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO |
| Molecular Weight | 217.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-5-fluoroacetophenone, 97% (CAS 1006-33-3)
- 1-(2-Bromo-4-fluorophenyl)ethanone (CAS 1006-39-9)
- 3’-Bromo-4’-fluoroacetophenone (CAS 1007-15-4)
- 3-Bromo-5-fluoroacetophenone, 97% (CAS 105515-20-6)
- 2-(4-Bromo-3-fluorophenyl)acetaldehyde (CAS 109346-85-2)
- 2-(3-Bromo-4-fluorophenyl)acetaldehyde (CAS 109346-89-6)
- 5-Bromo-2-fluorobenzimidamide (CAS 1100752-70-2)
- 4-Bromo-2-fluorobenzimidamide (CAS 1100752-71-3)
Recommended Standards
- 4-Bromo-2-fluoro-5-methylbenzaldehyde (CAS 916792-23-9)
- 4-Bromo-3-fluoroacetophenone, 97% (CAS 304445-49-6)
- 3-Bromo-4-fluorobenzimidamide (CAS 929960-29-2)
- 4-Bromo-3-fluorobenzimidamide (CAS 780721-73-5)
- 5-Fluorospiro[indoline-3,4'-piperidin]-2-one (CAS 1025662-38-7)
- 4-Chloro-3-fluorobenzenesulfonyl chloride (CAS 942035-77-0)
- (1,2,3-Thiadiazole-5-carbonyl)-d-valine (CAS 1568019-01-1)
- (4-Cyclopropoxy-5-methylpyridin-2-yl)methanamine (CAS 1243387-36-1)
- Ponfibrate - API Standards (CAS 53341-49-4)
- 3-(((1R,2S)-2-Fluorocyclopropyl)sulfonyl)benzonitrile (CAS 2375924-17-5)
- 1-(2-Ethylbutanoyl)azetidine-3-carboxylic acid (CAS 1343867-22-0)
- 3-((3-Chloro-4-methylphenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 477334-00-2)
- 4-(Methylsulfonyl)-3-(trifluoromethyl)benzonitrile (CAS 904311-38-2)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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