4-[(2-Chloro-6-fluorophenyl)methyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one CAS 626226-19-5
| CAS No. | 626226-19-5 |
| Molecular Formula | C15H11ClFNO2 |
| Molecular Weight | 291.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-[(2-Chloro-6-fluorophenyl)methyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-[(2-Chloro-6-fluorophenyl)methyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 626226-19-5), molecular formula C15H11ClFNO2 and molecular weight 291.70 g/mol, is a CATO reference standard with documented purity and traceability.
4-[(2-Chloro-6-fluorophenyl)methyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one (C15H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11ClFNO2 |
| Molecular Weight | 291.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-chloro-N-cyclopropyl-N-{[4-(trifluoromethyl)phenyl]methyl}acetamide (CAS 1258641-07-4)
- 2-Chloro-N-cyclopropyl-N-(3-(trifluoromethyl)benzyl)acetamide (CAS 1353963-68-4)
- 7-Chloro-4-(4-fluorophenyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1357778-48-3)
- 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(prop-2-yn-1-yl)pyridin-2(1H)-one (CAS 320424-25-7)
- 2'-Chloro-4'-methyl-5-nitro-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261967-52-5)
- 3'-Chloro-4'-methyl-3-nitro-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261979-62-7)
- N'-(2-Chloro-6-methyl-6H-pyrrolo[3,4-d]pyrimidin-4-yl)furan-2-carbohydrazide (CAS 1357086-97-5)
- 3-(2-Chloro-6-fluorophenyl)-5-[(E)-2-(dimethylamino)ethenyl]-1,2-oxazole-4-carbonitrile (CAS 1391943-62-6)
Recommended Standards
- Fluensulfone (CAS 318290-98-1)
- 2-Amino-5-chloro-α-[(1E)-2-cyclopropylethenyl]-α-(trifluoromethyl)-benzenemethanol (CAS 221177-51-1)
- 2-Amino-α-1-pentynyl-5-chloro-α-(trifluoromethyl)-benzenemethanol (CAS 1797114-07-8)
- Methyl 3-acetamido-5-(chlorosulfonyl)benzoate (CAS 1393542-98-7)
- N-methyl-2-phenoxyethan-1-amine hydrochloride (CAS 85262-76-6)
- N-(imidazo[1,2-a]pyridin-3-yl)acetamide (CAS 66358-09-6)
- Methyl 5-(4-methoxyphenyl)thiophene-2-carboxylate (CAS 69202-21-7)
- (6-Bromo-3-methoxypyridin-2-yl)methanol (CAS 905562-98-3)
- 6-Chloro-4-fluoro-2,3-dihydro-1H-inden-1-one (CAS 174603-49-7)
- Methyl (S)-2-(4-(4-chlorophenyl)-2-(hydroxymethyl)-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate (CAS 916491-91-3)
- 1-(1-Cyclohexyl-1h-pyrazol-4-yl)methanamine (CAS 1199773-51-7)
- 2-(3-Bromo-5-fluorophenoxy)acetonitrile (CAS 1379351-43-5)
- 2-(Prop-1-en-1-yl)phenol (CAS 23619-59-2)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com