Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate CAS 626226-42-4
| CAS No. | 626226-42-4 |
| Molecular Formula | C23H22F3N3O3S2 |
| Molecular Weight | 509.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate.
Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 626226-42-4), molecular formula C23H22F3N3O3S2 and molecular weight 509.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (C23H22F3N3O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 2-[3-amino-6-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-amido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H22F3N3O3S2 |
| Molecular Weight | 509.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)methyl)-4-(5-nitrothiophen-2-yl)-4H-pyran-3-carboxylate (CAS 445390-92-1)
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-54-7)
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(2,6-dimethylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332018-66-3)
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(m-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332155-26-7)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dichloro-2-(2,2,2-trifluoroacetamido)benzamide (CAS 154623-75-3)
- 3-Amino-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 400863-72-1)
- 3-Amino-4-(benzo[d][1,3]dioxol-5-yl)-N-(4-nitrophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332053-71-1)
- 3-Amino-N-(5-((2-chlorobenzyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-60-7)
Recommended Standards
- Ethyl 2-(2-((3-cyano-6-cyclopropyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 625377-49-3)
- Pyr-Phe-Leu-pNA (CAS 85901-57-1)
- Zidovudine EP Impurity J (CAS 29706-84-1)
- Posaconazole Impurity 58 (CAS CATO-C4X-120858)
- 5-Fluoro-1-(propan-2-yl)-1,3-diazinane-2,4,6-trione (CAS 1564748-31-7)
- FFN 511 (CAS 1004548-96-2)
- n-(Cyclopropylmethyl)-1-methyl-1h-pyrazol-4-amine (CAS 1156237-49-8)
- [(2R,8R)-2-fluorospiro[2,3,5,7-tetrahydro-1H-pyrrolizine-6,1'-cyclopropane]-8-yl]methanol (CAS 2837000-21-0)
- ethyl 2-(1,1-dioxo-1,4-thiazinan-4-yl)acetate (CAS 343334-01-0)
- 5-AMINO-4,5,6,7-TETRAHYDRO-1H-INDAZOLE (CAS 74197-16-3)
- 2-(4-Fluorophenoxy)-4-methylthiazole-5-carboxylic acid (CAS 1219539-96-4)
- 2-(Methoxymethyl)-6-methylpyrimidin-4(3H)-one hydrochloride (CAS 1354952-67-2)
- 3-(Bromomethyl)-1,5,5-trimethylimidazolidine-2,4-dione (CAS 159135-61-2)
- Peptide 442 (CAS CATO-CPTD788442)
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