2-((2-Fluorobenzyl)thio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 626228-62-4
| CAS No. | 626228-62-4 |
| Molecular Formula | C19H16F4N2S |
| Molecular Weight | 380.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((2-Fluorobenzyl)thio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (C19H16F4N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-((2-Fluorobenzyl)thio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 626228-62-4) is a high-purity analytical reference standard with the molecular formula C19H16F4N2S and a molecular weight of 380.40 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((2-Fluorobenzyl)thio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16F4N2S |
| Molecular Weight | 380.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- 1-(4-Fluorobenzyl)-5-oxo-N-(4-oxo-4H-chromen-2-yl)pyrrolidine-2-carboxamide (CAS 59749-50-7)
- 2-((3-Fluorobenzyl)thio)-3-phenyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 692287-48-2)
- 1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 59749-51-8)
- 3-(2-Fluorobenzyl)-6-iodoquinazolin-4(3H)-one (CAS 302913-41-3)
- (2-(2-((4-Fluorobenzyl)oxy)-5-(trifluoromethyl)phenyl)cyclopent-1-en-1-yl)boronic acid (CAS 612833-84-8)
- 4-[(4-Fluorobenzyl)oxy]benzyl 3-nitrobenzenecarboxylate (CAS 331461-75-7)
- 4-(4-Fluorobenzyl)-3-((4-methylbenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 866152-92-3)
- 5-((4-Fluorobenzyl)oxy)-4-oxo-N-(3-phenylpropyl)-4H-pyran-2-carboxamide (CAS 1021060-60-5)
Recommended Standards
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 912770-72-0)
- 2-Benzoyl-1-cyano-1,2-dihydroisoquinolin-7-yl benzoate (CAS 67335-02-8)
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-3-carboxylic acid (CAS 904816-50-8)
- 2-Phenylpentanedioic acid (CAS 2628-87-7)
- (R)-1-benzylpyrrolidine-2-carbonitrile (CAS 1260602-71-8)
- 5-(3-Fluorophenyl)-1,3,4-oxadiazole-2-carbaldehyde (CAS 944897-92-1)
- Ethyl 2-(6-cyclopropyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 938002-48-3)
- Methyl 4-(3-oxocyclohexyl)butanoate (CAS 147895-12-3)
- 4-(2-Pyridyl)phenol (CAS 51035-40-6)
- (5-(Pyridin-4-yl)thiophen-2-yl)boronic acid (CAS 2225176-80-5)
- 6-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-39-7)
- 5-Dodecanol (CAS 10203-33-5)
- 19725-12-3 3-(2-Methoxyphenyl)piperidine--hydrogen chloride (1/1) DTXSID20662846 (CAS 19725-12-3)
- Peptide Impurity 34 (CAS 21282-09-7)
Why CATO?
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