2-(Butylthio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 626228-67-9
| CAS No. | 626228-67-9 |
| Molecular Formula | C16H19F3N2S |
| Molecular Weight | 328.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Butylthio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(Butylthio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 626228-67-9) is a high-purity analytical reference standard with the molecular formula C16H19F3N2S and a molecular weight of 328.40 g/mol.
2-(Butylthio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (C16H19F3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Butylthio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H19F3N2S |
| Molecular Weight | 328.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Butylthio Standards
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- 1-Benzyl-2-(butylthio)-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione (CAS 3434-24-0)
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- 2-(sec-Butylthio)-6-(naphthalen-2-ylmethyl)pyrimidin-4(1H)-one (CAS 189057-61-2)
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Recommended Standards
- 2-((4-Fluorobenzyl)thio)-5-(4-methoxyphenyl)-1-methyl-1H-imidazole (CAS 932515-33-8)
- 2-(Propylsulfanyl)-4-(trifluoromethyl)-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridine-3-carbonitrile (CAS 626228-66-8)
- 1,3,5-Triphenylpentane-1,5-dione (CAS 6263-84-9)
- 2-Phenyl-4-((3-phenylprop-2-yn-1-yl)oxy)-4,5,6,7-tetrahydrobenzofuran (CAS 771477-54-4)
- 1-(2-Fluoro-5-nitrophenyl)propan-1-one (CAS 461037-07-0)
- 1,5-Dichloro-8-methoxyisoquinoline (CAS 2706823-15-4)
- 6-Chloro-4,4'-dimethyl-2,2'-bipyridine (CAS 1025763-34-1)
- 5-Bromo-2-cyano-4-(trifluoromethyl)benzenesulfonyl chloride (CAS 1805417-07-5)
- 3-(3-Fluorophenoxy)pyrazine-2-carboxylic acid (CAS 1228552-82-6)
- Eltrombopag Impurity 50 (CAS 29418-36-8)
- (R)-1-(4-(Trifluoromethoxy)phenyl)ethan-1-amine hydrochloride (CAS 1208989-29-0)
- 2-(Bromomethyl)-1-methoxyanthracene-9,10-dione (CAS 63965-46-8)
- 4-Bromopyrimidine-2-carbaldehyde (CAS 1378667-59-4)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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