3-Bromo-5-(trifluoromethyl)anisole CAS 627527-23-5
| CAS No. | 627527-23-5 |
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.03 g/mol gives 3-Bromo-5-(trifluoromethyl)anisole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Bromo-5-(trifluoromethyl)anisole (CAS 627527-23-5), a certified reference material (molecular formula C8H6BrF3O, MW 255.03 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-5-(trifluoromethyl)anisole (C8H6BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Bromo-5-(trifluoromethyl)anisole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene (CAS 106854-77-7)
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- 1-Bromo-3-methoxy-2-(trifluoromethyl)benzene (CAS 1214345-25-1)
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- 4-Bromo-1-methoxy-2-(trifluoromethyl)benzene (CAS 1514-11-0)
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- (3-Bromo-5-(trifluoromethyl)phenyl)methanol (CAS 172023-97-1)
Recommended Standards
- 3-Bromo-4-(trifluoromethyl)anisole (CAS 944901-07-9)
- 4-Bromo-2-(trifluoromethyl)benzenemethanol (CAS 932390-36-8)
- 2-Iodothiazole-5-carboxylic acid (CAS 2090961-67-2)
- 4-Bromo-2-methoxybenzotrifluoride (CAS 944805-63-4)
- (S)-2-Amino-2-(o-tolyl)ethan-1-ol hydrochloride (CAS 1917283-73-8)
- Mal-amido-PEG3-C1-NHS ester (CAS 2101206-45-3)
- (1S,2R,3S,4R,5R,6R)-5-(Hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2,3,4-triol (CAS 126661-83-4)
- 1-ethyl-4-iodo-5-nitro-1h-pyraZole (CAS 1354705-16-0)
- Methyl tert-butyl ether-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1173023-78-3)
- 2-(3-Fluorobenzoyl)-1-methyl-1h-imidazole (CAS 1247473-86-4)
- 3-(Bromomethyl)-2-chloro-5-fluoropyridine (CAS 1227573-95-6)
- 2-Chloro-1-[2,5-dimethyl-1-(1-phenylethyl)-1h-pyrrol-3-yl]ethan-1-one (CAS 784172-02-7)
- 2-Phenylpyrimidin-4-ol (CAS 127892-81-3)
- Peptide 437 (CAS CATO-CPTD788437)
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