3-(Bromomethyl)-2-chloro-5-fluoropyridine CAS 1227573-95-6
| CAS No. | 1227573-95-6 |
| Molecular Formula | C6H4BrClFN |
| Molecular Weight | 224.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Bromomethyl)-2-chloro-5-fluoropyridine is closely related to a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Bromomethyl)-2-chloro-5-fluoropyridine (CAS 1227573-95-6), molecular formula C6H4BrClFN and molecular weight 224.46 g/mol, is a CATO reference standard with documented purity and traceability.
3-(Bromomethyl)-2-chloro-5-fluoropyridine (C6H4BrClFN) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Bromomethyl)-2-chloro-5-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClFN |
| Molecular Weight | 224.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 2-(Bromomethyl)-6-chloro-3-fluoropyridine (CAS 1227509-98-9)
- 3-(Bromomethyl)-2-chloro-6-fluoropyridine (CAS 1227516-84-8)
- 4-(Bromomethyl)-3-chloro-5-fluoropyridine (CAS 1227563-95-2)
- 3-(Bromomethyl)-5-chloro-2-fluoropyridine (CAS 1227574-00-6)
- 4-(Bromomethyl)-2-chloro-3-fluoropyridine (CAS 1227585-77-4)
- 6-(Bromomethyl)-2-chloro-3-fluoropyridine (CAS 1227586-47-1)
- 2-(Bromomethyl)-3-chloro-5-fluoropyridine (CAS 1227586-53-9)
- 2-(Bromomethyl)-5-chloro-3-fluoropyridine (CAS 1227586-60-8)
Recommended Standards
- 3-Bromo-4-(chloromethyl)-5-fluoropyridine (CAS 1227573-06-9)
- 6-Bromo-2-(chloromethyl)-3-fluoropyridine (CAS 1227575-18-9)
- 5-Bromo-4-(chloromethyl)-2-fluoropyridine (CAS 1227562-25-5)
- 5-Bromo-3-chloromethyl-2-fluoropyridine (CAS 1227584-14-6)
- 1-(4-Chlorophenyl)-5-[(E)-[(4-fluorophenyl)methylidene]amino]-6-imino-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carbonitrile (CAS 1048915-26-9)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(3,4-difluorophenyl)acetamide (CAS 303091-74-9)
- 2-(Difluoromethyl)-6-methyl-5-nitropyridine-3-sulfonamide (CAS 1805436-39-8)
- 1-(2-Chloro-4-nitrophenyl)-1H-pyrrole (CAS 106981-58-2)
- 4-Bromo-7-methylpyrazolo[1,5-a]pyridine (CAS 1427364-72-4)
- 5-(4-Fluorophenyl)-4-(4-methylphenyl)-4h-1,2,4-triazole-3-thiol (CAS 54543-42-9)
- 1-(Dimethylamino)-4-(2-fluorophenoxy)pent-1-en-3-one (CAS 1164562-69-9)
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