7-Chloro-5-(2-Fluorophenoxy)-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One CAS 62903-61-1
| CAS No. | 62903-61-1 |
| Molecular Formula | C16H12ClFN2O2 |
| Molecular Weight | 318.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-5-(2-Fluorophenoxy)-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-Chloro-5-(2-Fluorophenoxy)-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One (CAS 62903-61-1) is a high-purity analytical reference standard with the molecular formula C16H12ClFN2O2 and a molecular weight of 318.73 g/mol.
Based on its molecular formula C16H12ClFN2O2, 7-Chloro-5-(2-Fluorophenoxy)-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 318.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-5-(2-Fluorophenoxy)-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClFN2O2 |
| Molecular Weight | 318.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Prop-2-yn-1-yl 3-chloro-4-((4-fluorobenzyl)oxy)benzoate (CAS 1706457-63-7)
- 3-(2-(Trifluoromethyl)pyrimidin-5-yl)propanoic acid (CAS 1216040-74-2)
- 5-Chlorothiazol-2-amine (CAS 41663-73-4)
- Rabenzazole (CAS 40341-04-6)
- 1-(3-Aminopiperidin-1-yl)propan-2-one (CAS 1251333-64-8)
- 7-chloro-5-methyl-6H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1935530-73-6)
- 1-(2-(6-Methoxy-2-methylpyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352497-69-8)
- 2-(6-methyloxan-2-yl)acetonitrile (CAS 343868-07-5)
- 1-(Quinolin-8-ylmethyl)-1h-pyrazol-3-amine (CAS 1183577-36-7)
- (R)-2-(1-Amino-2,2,2-trifluoroethyl)benzonitrile (CAS 1212964-69-6)
- Biotinyl-Neuropeptide W-23 (human) (CAS 1815618-09-7)
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