Dacomitinib Impurity 31 CAS CATO-C4X-208631
| CAS No. | CATO-C4X-208631 |
| Molecular Formula | C15H12ClFN4O |
| Molecular Weight | 318.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Dacomitinib Impurity 31 (CAS CATO-C4X-208631) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12ClFN4O and a molecular weight of 318.73 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Dacomitinib Impurity 31 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Dacomitinib Impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFN4O |
| Molecular Weight | 318.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Dacomitinib Standards
- Dacomitinib Impurity 4 (CAS 179552-75-1)
- Dacomitinib Impurity 40 (CAS CATO-C4X-208640)
- Dacomitinib Impurity 44 (CAS CATO-C4X-208644)
- Dacomitinib Impurity 43 (CAS CATO-C4X-208643)
- Dacomitinib Impurity 29 (CAS CATO-C4X-208629)
- Dacomitinib Impurity 26 (CAS CATO-C4X-208626)
- Dacomitinib Impurity 30 (CAS CATO-C4X-208630)
- Dacomitinib Impurity 39 (CAS CATO-C4X-208639)
Recommended Standards
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- Ethyl 2-(2-chloro-5-fluorophenyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1923068-94-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com