3-([1,1'-Biphenyl]-4-yl)-2-(3-chlorophenyl)-5-phenylisoxazolidine CAS 629643-19-2
| CAS No. | 629643-19-2 |
| Molecular Formula | C27H22ClNO |
| Molecular Weight | 411.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-([1,1'-Biphenyl]-4-yl)-2-(3-chlorophenyl)-5-phenylisoxazolidine (C27H22ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 3-([1,1'-Biphenyl]-4-yl)-2-(3-chlorophenyl)-5-phenylisoxazolidine (CAS 629643-19-2), a certified reference material (molecular formula C27H22ClNO, MW 411.92 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H22ClNO |
| Molecular Weight | 411.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Biphenyl Standards
- 1-((2-([1,1'-Biphenyl]-4-yl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid (CAS 881040-45-5)
- 7-{[1,1'-biphenyl]-4-yl}-2-[(3,4,4-trifluorobut-3-en-1-yl)sulfanyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 478043-71-9)
- 1-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)-4-(4-fluorophenyl)-1H-pyrazol-5-amine (CAS 956182-74-4)
- N1-([1,1'-Biphenyl]-4-yl)-N4,N4-diphenylbenzene-1,4-diamine (CAS 880800-19-1)
- 3-([1,1'-Biphenyl]-4-yl)-1-(4-((5-ethyl-4,5-dihydrothiazol-2-yl)amino)phenyl)prop-2-en-1-one (CAS 869714-67-0)
- [1,1'-Biphenyl]-3-yltriphenylsilane (CAS 13311-13-2)
- [1,1'-Biphenyl]-4-yltriphenylsilane (CAS 3172-34-7)
- N-([1,1'-biphenyl]-4-yl)-9-phenyl-9H-carbazol-3-amine (CAS 1002762-60-8)
Recommended Standards
- (R)-tert-butyl 3-((R)-(3-chlorophenyl)(2-ethoxy-2-oxoethoxy)methyl)piperidine-1-carboxylate (CAS 942142-76-9)
- Heptyl 6-chloro-2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 355421-23-7)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-[2-chloro-4-(tert-pentyl)phenoxy]-2-pyrrolidinecarboxylic acid (CAS 1354485-82-7)
- 5-((3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one (CAS 623936-02-7)
- 3-Cyano-4-cyclopropoxypicolinic acid (CAS 1243386-46-0)
- 3-(1-Isobutyrylpiperidin-4-yl)indolin-2-one (CAS 1790462-43-9)
- (r,e)-4-Phenylbut-3-en-2-amine (CAS 2089544-97-6)
- Ethyl 2-chloro-4,4,4-trifluoroacetoacetate (CAS 363-58-6)
- 5-Chloro-1-(2-fluorophenyl)-3-propyl-1h-pyrazole-4-carboxylic acid (CAS 1152978-92-1)
- 3-(3-(Benzyloxy)thiophen-2-yl)-4-methyl-5-(methylthio)-4H-1,2,4-triazole (CAS 343375-91-7)
- 4-(4-Methylphenyl)-2-pyrimidinethiol (CAS 477859-71-5)
- 6-Methyl-8-methylsulfanyl-imidazo[1,2-a]pyrazine (CAS 1094070-46-8)
- 5-Nitro-1,10-phenanthroline (CAS 4199-88-6)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com