diethyl 2-[(2-fluoroanilino)methylene]malonate CAS 63010-68-4
| CAS No. | 63010-68-4 |
| Molecular Formula | C14H16FNO4 |
| Molecular Weight | 281.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.28 g/mol gives diethyl 2-[(2-fluoroanilino)methylene]malonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
diethyl 2-[(2-fluoroanilino)methylene]malonate (CAS 63010-68-4), molecular formula C14H16FNO4 and molecular weight 281.28 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, diethyl 2-[(2-fluoroanilino)methylene]malonate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures diethyl 2-[(2-fluoroanilino)methylene]malonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16FNO4 |
| Molecular Weight | 281.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related diethyl Standards
- diethyl 2-[(4-fluoroanilino)methylene]malonate (CAS 26832-96-2)
- Diethyl 2-(4-nitrophenyl)malonate (CAS 10565-13-6)
- Diethyl (2-nitrophenyl)malonate (CAS 10565-14-7)
- Diethyl 2-(((1,3-dimethyl-1H-pyrazol-5-yl)amino)methylene)malonate (CAS 20481-33-8)
- 1,3-diethyl 2-(propane-1-sulfonamido)propanedioate (CAS 1155138-86-5)
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- Diethyl 3-Bromopropylmalonate (CAS 10149-21-0)
Recommended Standards
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- methyl 2-(4-fluorophenyl)-4-quinolinecarboxylate (CAS 327092-77-3)
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- (4-Methyl-3-nitrophenyl)methanesulfonyl chloride (CAS 1250191-81-1)
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- 5-Oxo-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid (CAS 56461-21-3)
- 2-Methyl-5-(pyrrolidin-1-ylsulfonyl)indoline (CAS 944886-96-8)
- 2-(1-Amino-3-methylbutyl)pyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1708250-60-5)
- 2-(5-Bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-N-isopropylacetamide (CAS 923208-34-8)
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- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
Why CATO?
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