Ethyl 2-(2-chloroacetamido)benzoate CAS 6307-66-0
| CAS No. | 6307-66-0 |
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 2-(2-chloroacetamido)benzoate (C11H12ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ethyl 2-(2-chloroacetamido)benzoate (CAS 6307-66-0), a certified reference material (molecular formula C11H12ClNO3, MW 241.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO3 |
| Molecular Weight | 241.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Methyl 2-(2-chloroacetamido)-2-phenylacetate (CAS 100508-78-9)
- 3-(3-(2-Chloroacetamido)phenyl)propanoic acid (CAS 1221792-58-0)
- 3-((2-Chloroacetamido)methyl)-4-methylbenzoic acid (CAS 727673-69-0)
- 3-(2-Chloroacetamido)-3-phenylpropanoic acid (CAS 607737-27-9)
- 3-(4-(2-Chloroacetamido)phenyl)propanoic acid (CAS 500336-83-4)
- Ethyl 4-(2-chloroacetamido)benzoate (CAS 26226-72-2)
- Methyl 3-(2-chloroacetamido)-4-methylbenzoate (CAS 54941-43-4)
- Methyl 4-[(2-chloroacetamido)methyl]benzoate (CAS 379255-44-4)
Recommended Standards
- Ethyl 2-((4-chlorobenzyl)amino)-2-oxoacetate (CAS 6951-43-5)
- Ethyl 2-amino-2-[2-(4-chlorophenyl)hydrazono]acetate (CAS 56462-76-1)
- Ethyl 2-((4-chloro-2-methylphenyl)amino)-2-oxoacetate (CAS 69066-14-4)
- Ethyl 2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4-carboxylate (CAS 944902-79-8)
- 3-(1-Benzofuran-2-yl)-1,2,4-oxadiazole-5-thiol (CAS 1343081-94-6)
- 2-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-(ethyl)amino]-1-ethanol (CAS 1220033-21-5)
- 5-(4-Chlorophenyl)-N-cyclopentyl-2-methylpyrimidin-4-amine (CAS 917896-12-9)
- Tetrahydro-5-methyl-3-furanmethanol (CAS 22600-86-8)
- methyl (3R)-3-fluoropyrrolidine-3-carboxylate hydrochloride (CAS 2306253-52-9)
- 1,1-Diethoxybutan-2-one (CAS 6136-92-1)
- Topramezone Impurity 1 (CAS CATO-C4X-35031)
- Trans-5-(2-chlorophenyl)-3-methyl-4,5-dihydroisoxazole-4-carbonitrile (CAS 62219-87-8)
- 2,5-Dioxo-2,5-dihydrofuran-3,4-diyl dibenzoate (CAS 134-00-9)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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