4-(4-Chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine CAS 63156-78-5
| CAS No. | 63156-78-5 |
| Molecular Formula | C11H9ClF3N3 |
| Molecular Weight | 275.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (CAS 63156-78-5) is a high-purity analytical reference standard with the molecular formula C11H9ClF3N3 and a molecular weight of 275.66 g/mol.
Structurally, 4-(4-Chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (C11H9ClF3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 275.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9ClF3N3 |
| Molecular Weight | 275.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-2-methyl-5-(trifluoromethyl)-2,3-dihydro-1h-pyrazol-3-imine (CAS 1365630-37-0)
- 2-(3-Chlorophenyl)-4-fluoroisoindoline-1,3-dione (CAS 917746-18-0)
- Ethyl 1-(2-chlorophenyl)-5-cyano-1H-pyrazole-3-carboxylate (CAS 1269291-83-9)
- 4-(4-Chlorophenyl)-3,6-dimethylisoxazolo[3,4-d]pyridazin-7(6H)-one (CAS 135126-70-4)
- Methyl 2-(2-chlorophenyl)-4H-furo[3,2-b]pyrrole-5-carboxylate (CAS 1713640-18-6)
- 2-((2-Chlorophenyl)carbamoyl)benzoic acid (CAS 6273-12-7)
- 2-(4-Chlorophenyl)-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione (CAS 43069-79-0)
- 3-[(2-chlorophenyl)methyl]-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol (CAS 333407-55-9)
Recommended Standards
- 3-Chloro-N-methyl-N-(1H-pyrrol-1-yl)-5-(trifluoromethyl)pyridin-2-amine (CAS 338400-00-3)
- 5-(4-Chloro-3-fluorophenyl)-1H-indole-2,3-dione (CAS 893736-17-9)
- N-(3-chloro-2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 478261-68-6)
- 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine (CAS 374559-96-3)
- N-Cyclopropyl-N-methylformamide (CAS 1403483-62-4)
- tert-Butyl 5-chloro-6-(trifluoromethyl)-1H-indole-1-carboxylate (CAS 1209101-50-7)
- (6-(3-Hydroxyoxetan-3-yl)pyridin-3-yl)boronic acid (CAS 1207758-97-1)
- 2-[(E)-2-[(4-Methoxyphenyl)amino]ethenyl]-4-(trifluoromethyl)-1,3-thiazole-5-carbonitrile (CAS 339026-52-7)
- 2-(3-Oxabicyclo[3.1.0]hexan-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2489456-36-0)
- 2-[5-Methoxy-2-nitro-4-(trifluoromethyl)phenyl]-acetic acid (CAS 1190198-33-4)
- 3-(2-Phenyloxazol-4-yl)benzo[d]isoxazole-5-carboxylic acid (CAS 1422062-93-8)
- N-Allyl-N-(3-methyl-1,2,4-thiadiazol-5-yl)-2-phenylacetamide (CAS 62347-34-6)
- 2-(3',3-Difluorobiphenyl-5-yl)acetonitrile (CAS 1214391-05-5)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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