Raltitrexed Impurity 6 CAS 6317-37-9
| CAS No. | 6317-37-9 |
| Molecular Formula | C5H3NO4S |
| Molecular Weight | 173.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Raltitrexed Impurity 6 (CAS 6317-37-9, C5H3NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carbohydrate-derived structure, an amide group, a sulfone group, Raltitrexed Impurity 6 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 173.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C5H3NO4S |
| Molecular Weight | 173.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Raltitrexed Standards
- Raltitrexed Impurity 5 (CAS 4282-31-9)
- Raltitrexed Impurity 2 (CAS 18731-19-6)
- Raltitrexed Impurity 45 (CAS CATO-C4X-138645)
- Raltitrexed Impurity 44 (CAS CATO-C4X-138644)
- Raltitrexed Impurity 18 (CAS CATO-C4X-138618)
- Raltitrexed Impurity 1 (CAS 1378372-01-0)
- Raltitrexed Impurity 4 (CAS 39978-57-9)
- Raltitrexed Impurity 46 (CAS CATO-C4X-138646)
Recommended Standards
- 5374-29-8 CTK1H3690 ethyl N-[[(Z)-(3-ethoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]amino]carbamate (CAS 5374-29-8)
- TEPA (CAS 545-55-1)
- Thiazole-4,5-dicarboxylic acid (CAS 22358-80-1)
- 2-Amino-1-(3,4-difluorophenyl)ethanol (CAS 10145-04-7)
- Ketoprofen Impurity 88 (CAS 1984110-22-6)
- Tenofovir Disoproxil Impurity 45 (CAS 35273-90-6)
- Axitinib Impurity 90 (CAS CATO-C4X-107190)
- 1,2-Diazaspiro[2.4]hept-1-ene-5-carboxylic acid (CAS 2098110-76-8)
- 4,5,6-TRIMETHOXY-1H-INDOLE (CAS 30448-04-5)
- (S)-2-(5,6-dichloro-1,3-dioxoisoindolin-2-yl)-3-methylbutanoic acid (CAS 111104-28-0)
- n-Cyclohexyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 444923-32-4)
- (9H-fluoren-9-yl)methyl (S)-4-isobutyl-5-oxooxazolidine-3-carboxylate (CAS 864966-70-1)
- 1-(6-Ethoxypyridin-2-yl)ethanone (CAS 21190-90-9)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
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