2-Phenyl-4-(p-tolyloxy)isoindoline-1,3-dione CAS 63181-79-3
| CAS No. | 63181-79-3 |
| Molecular Formula | C21H15NO3 |
| Molecular Weight | 329.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Phenyl-4-(p-tolyloxy)isoindoline-1,3-dione (CAS 63181-79-3) is a high-purity analytical reference standard with the molecular formula C21H15NO3 and a molecular weight of 329.35 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 2-Phenyl-4-(p-tolyloxy)isoindoline-1,3-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H15NO3 |
| Molecular Weight | 329.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Amino-7-(3,4,5-trimethoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 364380-99-4)
- 2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione (CAS 63196-28-1)
- 2-{[5-(2-fluorophenyl)-4-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 730973-18-9)
- 3-(((1-Hydroxynaphthalen-2-yl)methylene)amino)-2-methylquinazolin-4(3H)-one (CAS 371120-48-8)
- (S)-1-((2S,3S,4aR,5R,7S,8S,8aS)-8-(Benzyloxy)-2,3,7-trimethoxy-2,3-dimethylhexahydro-2H-pyrano[3,4-b][1,4]dioxin-5-yl)prop-2-en-1-ol (CAS 362518-37-4)
- 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl azide 3,4,6-Triacetate (CAS 102816-24-0)
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