2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione CAS 63196-28-1

Purity 97%+In StockPharmaceutical Standards
CAS No.63196-28-1
Molecular FormulaC21H15NO3
Molecular Weight329.35 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione CAS 63196-28-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione.

2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione (CAS 63196-28-1) is a high-purity analytical reference standard with the molecular formula C21H15NO3 and a molecular weight of 329.35 g/mol.

Based on its molecular formula C21H15NO3, 2-Phenyl-5-(p-tolyloxy)isoindoline-1,3-dione contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H15NO3
Molecular Weight329.35 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1975
Nitrogen Atoms1

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