Ascorbic Acid Impurity 1 CAS 63247-05-2
| CAS No. | 63247-05-2 |
| Molecular Formula | C22H36O7 |
| Molecular Weight | 412.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ascorbic Acid Impurity 1 (CAS 63247-05-2, C22H36O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ascorbic Acid Impurity 1 (C22H36O7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 412.52 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ascorbic Acid Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H36O7 |
| Molecular Weight | 412.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Ascorbic Standards
- Ascorbic Acid Impurity 2 (CAS CATO-C4X-31442)
- L-Ascorbic Acid 6-Stearate (CAS 10605-09-1)
- L-Ascorbic acid 2-phosphate xsodium salt (CAS 109620-90-8)
- L-Ascorbic Acid 2-Phosphate Sesquimagnesium Salt Hydrate (CAS 113170-55-1)
- Ascorbic Acid Impurity 43 (CAS 20229-76-9)
- D-Ascorbic Acid Impurity 19 (CAS 67776-07-2)
- Ascorbic Acid EP Impurity D (CAS 3031-98-9)
- Ascorbic Acid EP Impurity H (CAS 122046-79-1)
Recommended Standards
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- Pitavastatin Impurity 131 (CAS CATO-C4X-1037131)
- Pentoxifylline EP Impurity J (CAS 874747-30-5)
- Methyl 3-bromofuran-2-carboxylate (CAS 59862-77-0)
- 5-Oxoundecanoic acid (CAS 16424-28-5)
- 4-(2-Nitrovinyl)-1H-imidazole (CAS 948905-48-4)
- 2-(5-Chlorothiophen-2-yl)-2-methoxyethan-1-amine (CAS 1250927-84-4)
- 2082-76-0 AR-1I9864 ethyl n-[(benzyloxy)carbonyl]glycylphenylalanylglycinate (CAS 2082-76-0)
- 2-(4-(Difluoromethyl)-3-nitro-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile (CAS 1806049-60-4)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com