Pentoxifylline EP Impurity J CAS 874747-30-5
| CAS No. | 874747-30-5 |
| Molecular Formula | C26H34N8O5 |
| Molecular Weight | 538.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pentoxifylline EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Pentoxifylline EP Impurity J (CAS 874747-30-5), a pharmacopoeial impurity reference standard (molecular formula C26H34N8O5, MW 538.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Pentoxifylline EP Impurity J (C26H34N8O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H34N8O5 |
| Molecular Weight | 538.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 8 |
Related Pentoxifylline Standards
- Pentoxifylline impurity 34 (CAS CATO-C4X-172834)
- Pentoxifylline impurity 36 (CAS CATO-C4X-172836)
- Pentoxifylline EP Impurity K (CAS 74857-22-0)
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- Pentoxifylline EP Impurity H (CAS 200556-62-3)
- Pentoxifylline Impurity N2 (CAS 1243654-85-4)
- Pentoxifylline Impurity 26 (CAS CATO-C4X-172826)
- Pentoxifylline Impurity N4 (CAS 84321-40-4)
Recommended Standards
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- Dexamethasone impurity 81 (CAS CATO-C4X-116581)
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- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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