2-((2-Aminopyrimidin-4-yl)carbamoyl)benzoic acid CAS 63271-77-2
| CAS No. | 63271-77-2 |
| Molecular Formula | C12H10N4O3 |
| Molecular Weight | 258.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2-Aminopyrimidin-4-yl)carbamoyl)benzoic acid.
2-((2-Aminopyrimidin-4-yl)carbamoyl)benzoic acid (CAS 63271-77-2) is a high-purity analytical reference standard with the molecular formula C12H10N4O3 and a molecular weight of 258.23 g/mol.
The molecular framework of 2-((2-Aminopyrimidin-4-yl)carbamoyl)benzoic acid (C12H10N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10N4O3 |
| Molecular Weight | 258.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 4 |
Related Aminopyrimidin Standards
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- 4-((2-Aminopyrimidin-4-yl)amino)benzenesulfonamide (CAS 2153-13-1)
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- 2-(2-Aminopyrimidin-4-yl)-4-bromophenol (CAS 925003-46-9)
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Recommended Standards
- 11-Methyl-8,14,16-trioxatetracyclo[8.6.0.0^{2,7}.0^{11,15}]hexadeca-1(10),2,4,6-tetraene-9,13-dione (CAS 866157-77-9)
- 2-((3-Nitrophenyl)amino)benzoic acid (CAS 27693-70-5)
- 1,7-Dihydroxy-4-methoxy-9H-xanthen-9-one (CAS 87339-76-2)
- 2-((4-Nitrophenyl)amino)benzoic acid (CAS 7221-31-0)
- 4-Desacetyl-2-debenzoyl-[2,4]-oxol Paclitaxel (CAS 159500-49-9)
- (S)-5-(2,6-difluorophenyl)pyrrolidin-2-one (CAS 1181818-11-0)
- (3E,5E)-3,5-Bis[(3-chlorophenyl)methylidene]-1-methylpiperidin-4-one (CAS 54237-29-5)
- N-(4-hydroxycyclohexyl)-2-(methylamino)acetamide (CAS 1016685-50-9)
- (11bR)-2,6-Dibromo-N,N-bis((R)-1-phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 1642864-94-5)
- 2-(Methylamino)ethyl acetate (CAS 26921-43-7)
- Imrecoxib Impurity 25 (CAS CATO-C4X-237925)
- 57446-02-3 3,4-Dihydro-2H-pyrano[3,2-c]pyridine DTXSID20574112 (CAS 57446-02-3)
- Tetrakis(4-nitrophenyl)methane (CAS 60532-62-9)
- D-[Ser]8-Semaglutide (CAS CATO-C4X-2226207)
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