2-(Methylthio)-1H-imidazo[4,5-b]pyridine CAS 63277-46-3
| CAS No. | 63277-46-3 |
| Molecular Formula | C7H7N3S |
| Molecular Weight | 165.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Methylthio)-1H-imidazo[4,5-b]pyridine (C7H7N3S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-(Methylthio)-1H-imidazo[4,5-b]pyridine (CAS 63277-46-3), a certified reference material (molecular formula C7H7N3S, MW 165.22 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7N3S |
| Molecular Weight | 165.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 2-(2-(Methylthio)pyrimidin-4-yl)acetonitrile (CAS 897648-40-7)
- 2-(Methylthio)-3H-imidazo[4,5-c]pyridine (CAS 7397-69-5)
- 2-(Methylthio)-7H-pyrrolo[2,3-d]pyrimidine (CAS 93366-87-1)
- 3-(Methylthio)-[1,2,4]triazolo[4,3-a]pyridine (CAS 4922-86-5)
- 4-(Methylthio)-1H-pyrazolo[3,4-b]pyridine (CAS 49834-66-4)
- 4-Methyl-2-(methylthio)-5-pyrimidinecarbonitrile (CAS 89079-62-9)
- 6-(Methylthio)imidazo[1,2-b]pyridazine (CAS 61582-31-8)
- 6-Methyl-2-(methylthio)pyrimidine-4-carbonitrile (CAS 65735-62-8)
Recommended Standards
- 2-(1-methyl-1H-pyrazol-3-yl)-1,3-thiazole (CAS 648408-55-3)
- 2-(1H-Imidazol-1-yl)thiophen-3-amine (CAS 615535-07-4)
- 2-Methylthiazolo[5,4-b]pyridin-6-amine (CAS 857969-72-3)
- 1-Methyl-1H-imidazo[4,5-c]pyridine-2-thiol (CAS 7321-94-0)
- 3-Bromo-2,4,6-trifluorobenzoic acid (CAS 1160573-12-5)
- 2-(5-(2-Fluorophenyl)isoxazol-3-yl)-N-(5-methylisoxazol-3-yl)acetamide (CAS 1105217-16-0)
- 2-(3,4-Difluorophenyl)-5-nitro-1H-benzo[d]imidazole (CAS 99585-47-4)
- (2-Methoxybenzyl)(4-pyridinylmethyl)amine hydrobromide (CAS 1609396-25-9)
- 1-(Furan-2-yl)heptan-1-one (CAS 5466-40-0)
- 3-Chloro-N2-methylpyridine-2,5-diamine (CAS 813424-20-3)
- 2-Amino-4-(4-chlorophenyl)-7-methyl-3-(phenylsulfonyl)-4H,5H-pyrano[4,3-b]pyran-5-one (CAS 860611-38-7)
- 4-Bromo-5-fluoro-2,3-dihydro-1H-inden-1-ol (CAS 1443652-82-1)
- (1S,3R,5R)-2-(tert-butoxycarbonyl)-6,6-difluoro-2-azabicyclo[3.1.0]Hexane-3-carboxylic acid (CAS 2165338-56-5)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
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