4-(Methylthio)-1H-pyrazolo[3,4-b]pyridine CAS 49834-66-4
| CAS No. | 49834-66-4 |
| Molecular Formula | C7H7N3S |
| Molecular Weight | 165.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Methylthio)-1H-pyrazolo[3,4-b]pyridine (CAS 49834-66-4), molecular formula C7H7N3S and molecular weight 165.22 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Methylthio)-1H-pyrazolo[3,4-b]pyridine (C7H7N3S) contains a nitrile group, sulfur-containing functionality, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 165.22 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7N3S |
| Molecular Weight | 165.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 2-(2-(Methylthio)pyrimidin-4-yl)acetonitrile (CAS 897648-40-7)
- 2-(Methylthio)-1H-imidazo[4,5-b]pyridine (CAS 63277-46-3)
- 2-(Methylthio)-3H-imidazo[4,5-c]pyridine (CAS 7397-69-5)
- 2-(Methylthio)-7H-pyrrolo[2,3-d]pyrimidine (CAS 93366-87-1)
- 3-(Methylthio)-[1,2,4]triazolo[4,3-a]pyridine (CAS 4922-86-5)
- 4-Methyl-2-(methylthio)-5-pyrimidinecarbonitrile (CAS 89079-62-9)
- 6-(Methylthio)imidazo[1,2-b]pyridazine (CAS 61582-31-8)
- 6-Methyl-2-(methylthio)pyrimidine-4-carbonitrile (CAS 65735-62-8)
Recommended Standards
- 3-Methylimidazo[1,5-a]pyrazine-8-thiol (CAS 784082-29-7)
- 4-(Thiophen-2-yl)-1H-imidazol-2-amine (CAS 76507-19-2)
- 3-Methyl-3H-imidazo[4,5-b]pyridine-2-thiol (CAS 32282-08-9)
- 4-(Thiophen-2-yl)-1h-pyrazol-5-amine (CAS 91447-40-4)
- n-(Piperidin-4-yl)pyridine-2-carboxamide dihydrochloride (CAS 1177279-96-7)
- 2,4,5-Tribromo-1-propyl-1H-imidazole (CAS 31250-78-9)
- 2,4-Diamino-6-chlorophenol (CAS 13066-98-3)
- 2-Methoxypropyl Acetate (CAS 70657-70-4)
- 2-((((8R,9S,13S,14S,E)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-ylidene)amino)oxy)acetic acid (CAS 693227-00-8)
- Methyl 4-(4-(thiazol-2-yloxy)-[1,4'-bipiperidine]-1'-carbonyl)benzoate (CAS 1705742-64-8)
- 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline (CAS 1701-25-3)
- 2-(2-Fluoro-5-methylphenoxy)acetic acid (CAS 1394793-36-2)
- (S)-3-((S)-2-(4,4-Dimethyl-2,5-dioxo-3-(4-(3-(o-tolyl)ureido)benzyl)imidazolidin-1-yl)-4-methylpentanamido)-3-phenylpropanoic acid (CAS 479203-71-9)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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