4-Bromo-3-hydroxythiophene-2-carboxylic acid CAS 634187-30-7
| CAS No. | 634187-30-7 |
| Molecular Formula | C5H3BrO3S |
| Molecular Weight | 223.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-3-hydroxythiophene-2-carboxylic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-3-hydroxythiophene-2-carboxylic acid (CAS 634187-30-7), molecular formula C5H3BrO3S and molecular weight 223.04 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C5H3BrO3S, 4-Bromo-3-hydroxythiophene-2-carboxylic acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3BrO3S |
| Molecular Weight | 223.04 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- 3-bromo-2-isocyanatobenzonitrile (CAS 1261508-23-9)
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Recommended Standards
- 4’-Cyanobiphenyl-4-boronic Acid (CAS 406482-73-3)
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- 4-Iodo-1-methyl-1,2,3,6-tetrahydropyridine (CAS 1196146-99-2)
- (2-(3-Hydroxypyrrolidin-1-yl)-4-methylpyrimidin-5-yl)boronic acid (CAS 2225152-74-7)
- 8-Hydroxy-2-(2-(thiophen-3-yl)vinyl)quinoline-7-carboxylic acid (CAS 765304-43-6)
- (R)-1-(3-chloro-5-methylphenyl)-2-methylpropan-1-amine (CAS 1213351-59-7)
- Methyl (Z)-3-(1-naphthyl)-2-propenoate (CAS 70556-71-7)
- 4-(3-Oxopiperazin-1-yl)pyridine-2-carboxylic acid hydrochloride (CAS 1797548-50-5)
- (S)-1-(tert-Butoxycarbonyl)-2-(2-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid (CAS 1217741-53-1)
- 1-(4-Fluorophenyl)-3-(pyridin-2-ylsulfanyl)propan-1-one (CAS 1157733-02-2)
- 1-(pyridin-4-yl)cyclohexane-1-carboxamide (CAS 682739-20-4)
- 2-(5-bromo-2-fluorophenyl)-2-methylpropanenitrile (CAS 913719-91-2)
- 1-(1,3-Thiazol-2-yl)piperidine-4-carboxylic acid (CAS 874623-60-6)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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