4-Chloro-2,3,6-trifluoropyridine CAS 63489-53-2
| CAS No. | 63489-53-2 |
| Molecular Formula | C5HClF3N |
| Molecular Weight | 167.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 167.52 g/mol gives 4-Chloro-2,3,6-trifluoropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-2,3,6-trifluoropyridine (CAS 63489-53-2), molecular formula C5HClF3N and molecular weight 167.52 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C5HClF3N, 4-Chloro-2,3,6-trifluoropyridine contains a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 167.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2,3,6-trifluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5HClF3N |
| Molecular Weight | 167.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2,4,6-trifluoropyridine (CAS 1682-79-7)
- 2-Chloro-3,5,6-trifluoropyridine (CAS 344324-99-8)
- 3-Chloro-2,5,6-trifluoropyridine (CAS 2879-42-7)
- 4-Chloro-2,3,5-trifluoropyridine (CAS 914636-17-2)
- 5-Chloro-2,3,4-trifluoropyridine (CAS 52208-55-6)
- 4-Chloro-1-(difluoromethyl)-1h-pyrazol-3-amine (CAS 1344356-16-6)
- Ethyl 2-Chloro-2-nitroacetate (CAS 14011-27-9)
- 5-Chloro-1,1-dioxo-isothiazol-3-one (CAS 1239320-63-8)
Recommended Standards
- 4-(Chloromethyl)-5-(difluoromethyl)oxazole (CAS 2006920-94-9)
- Dichloromethanesulfinyl chloride (CAS 62479-74-7)
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- 2,2,2-Trichloro-1,1-ethanediol-1,1-d2 (CAS 19220-07-6)
- 3,5-BIbromo-2,6-difluorobenzaldehyde (CAS 1803713-69-0)
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- Topiroxostat-d4 (CAS CATO-C4X-105533)
- Ethyl 4-(pyridin-2-yl)thiazole-2-carboxylate (CAS 886370-87-2)
- 1,1-Dimethyl-2-(1-piperidinyl)ethylamine dihydrochloride (CAS 1089314-24-8)
- Rosuvastatin Impurity 139 (CAS CATO-C4X-1169139)
- 6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl benzoate (CAS 877635-24-0)
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