2,3,6-Trifluoropyridin-4-amine CAS 63489-55-4
| CAS No. | 63489-55-4 |
| Molecular Formula | C5H3F3N2 |
| Molecular Weight | 148.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,3,6-Trifluoropyridin-4-amine (C5H3F3N2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,3,6-Trifluoropyridin-4-amine (CAS 63489-55-4), molecular formula C5H3F3N2 and molecular weight 148.09 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,3,6-Trifluoropyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3F3N2 |
| Molecular Weight | 148.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoropyridin Standards
- 2,3,5-Trifluoropyridin-4-amine (CAS 105252-95-7)
- 4,5,6-Trifluoropyridin-2-amine (CAS 1805509-87-8)
- 3,4,6-Trifluoropyridin-2-amine (CAS 63489-59-8)
- 3,5,6-Trifluoropyridin-2-amine (CAS 3534-50-7)
- (2,3,6-Trifluoropyridin-4-yl)methanamine (CAS 2170219-47-1)
- (2,5,6-Trifluoropyridin-3-yl)methanamine (CAS 771582-56-0)
- 2-(3,5,6-Trifluoropyridin-2-yl)acetic acid (CAS 1119450-11-1)
- 1-(3,5,6-trifluoropyridin-2-yl)piperazine (CAS 1226516-20-6)
Recommended Standards
- (5R,6R)-5-Fluoro-6-hydroxydihydropyrimidine-2,4(1H,3H)-dione (CAS 93713-25-8)
- 2-Fluoro-3-ureidoacrylic acid (CAS 76831-42-0)
- 2,4,6-Trifluoro-5-methylpyrimidine (CAS 18260-60-1)
- 5-(Trifluoromethyl)pyrimidine (CAS 176214-12-3)
- Potassium hexanitritorhodate(III) (CAS 17712-66-2)
- 5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 827588-61-4)
- Ethyl 5-(bromomethyl)thiazole-2-carboxylate (CAS 960235-24-9)
- Neo-Tetrazolium Diformazan (CAS 21520-87-6)
- N-Ethyl-N-methylpropane-1,3-diamine (CAS 74247-23-7)
- 4-Bromo-3-(trifluoromethyl)pyridine (CAS 1060801-89-9)
- 2,4-dichloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 129872-81-7)
- 2-(4-Benzoylphenyl)-2-(4-chlorophenyl)acetamide (CAS 338965-26-7)
- Cryptopine (CAS 482-74-6)
- Peptide 432 (CAS CATO-CPTD788432)
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