4-Chloro-3,5,6-trifluoropyridin-2-amine CAS 63489-56-5

Purity 97%+In StockPharmaceutical Standards
CAS No.63489-56-5
Molecular FormulaC5H2ClF3N2
Molecular Weight182.53 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3,5,6-trifluoropyridin-2-amine CAS 63489-56-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 182.53 g/mol gives 4-Chloro-3,5,6-trifluoropyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Chloro-3,5,6-trifluoropyridin-2-amine (CAS 63489-56-5), molecular formula C5H2ClF3N2 and molecular weight 182.53 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C5H2ClF3N2, 4-Chloro-3,5,6-trifluoropyridin-2-amine contains a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 182.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-3,5,6-trifluoropyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H2ClF3N2
Molecular Weight182.53 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1975
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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