2-Amino-5-(4-chloro-2-fluorophenyl)-1,3,4-thiadiazole CAS 635301-09-6
| CAS No. | 635301-09-6 |
| Molecular Formula | C8H5ClFN3S |
| Molecular Weight | 229.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Amino-5-(4-chloro-2-fluorophenyl)-1,3,4-thiadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Amino-5-(4-chloro-2-fluorophenyl)-1,3,4-thiadiazole (CAS 635301-09-6), molecular formula C8H5ClFN3S and molecular weight 229.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Amino-5-(4-chloro-2-fluorophenyl)-1,3,4-thiadiazole (C8H5ClFN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5ClFN3S |
| Molecular Weight | 229.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
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- 2-BUtoxy-4-chloro-1-nitrobenzene (CAS 401622-27-3)
- 2,2'-(1-Methyl-1,2-Ethanediylidene) Bis(Hydrazinecarboximidamide) Dihydrochloride Hydrate (CAS 24968-67-0)
- 1-(2-Amino-5-((4-chlorophenyl)ethynyl)pyrimidin-4-yl)piperidin-4-ol (CAS 393855-99-7)
- (S)-1-(Oxazol-4-yl)ethan-1-amine (CAS 1563544-10-4)
- trans-4-((Dimethylamino)methyl)piperidin-3-ol dihydrochloride (CAS 1609407-11-5)
- (S)-N-Nitroso Anatabine-d4 (CAS 1426174-82-4)
- Methyl 2-{4-[4-amino-2-(trifluoromethyl)phenoxy]-phenyl}acetate (CAS 946697-79-6)
- 5-Amino-2,4-di-tert-butylphenyl methyl carbonate (CAS 1182822-31-6)
- 3-Cyclopropyl-2,2-difluoropropanoic acid (CAS 1556048-70-4)
- 2,4,6-Triethylbenzaldehyde (CAS 16688-89-4)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com