2,4-Dichloro-5-(thiophen-3-yl)pyrimidine CAS 63558-75-8
| CAS No. | 63558-75-8 |
| Molecular Formula | C8H4Cl2N2S |
| Molecular Weight | 231.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dichloro-5-(thiophen-3-yl)pyrimidine (C8H4Cl2N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2,4-Dichloro-5-(thiophen-3-yl)pyrimidine (CAS 63558-75-8), molecular formula C8H4Cl2N2S and molecular weight 231.10 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Dichloro-5-(thiophen-3-yl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2N2S |
| Molecular Weight | 231.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,4-Dichloro-5-(thiophen-2-yl)pyrimidine (CAS 63558-74-7)
- 4,6-Dichloro-2-(thiophen-2-yl)pyrimidine (CAS 57059-13-9)
- 4,6-Dichloro-2-(thiophen-3-yl)pyrimidine (CAS 57059-14-0)
- 8,9-Dichloro-2,3,4,5-tetrahydro-1-benzoxepin-5-one (CAS 1094253-83-4)
- 4,6-Dichloro-3-isopropyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1211580-39-0)
- 4,6-dichloro-1-propyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1251465-05-0)
- 2-(4,6-Dichloro-2-cyclopropylpyrimidin-5-yl)acetaldehyde (CAS 1311275-29-2)
- 5,7-Dichloro-2-propyl-2H-pyrazolo[4,3-d]pyrimidine (CAS 1357087-31-0)
Recommended Standards
- 2,6-Bis(trifluoromethyl)pyridin-4-ol (CAS 43150-55-6)
- 2,4,6-Tris(difluoromethyl)-1,3,5-triazine (CAS 369-22-2)
- 2-Bromo-1,3-diethyl-5-fluorobenzene (CAS 2143028-85-5)
- 2-(4-Methylstyryl)-1,3,6,2-dioxazaborocane (CAS 608534-31-2)
- 2-(3,4-Diethoxybenzoyl)benzoic acid (CAS 234780-28-0)
- 5-Bromo-2-chloro-3-ethynylpyridine (CAS 1256791-73-7)
- 4-Chloro-2-isopropylpyridin-3-amine (CAS 2397623-65-1)
- {3-iodoimidazo[1,2-a]pyridin-7-yl}methanol (CAS 1036990-66-5)
- (5-(Trifluoromethyl)pyridin-2-yl)methanamine hydrochloride (CAS 871826-12-9)
- 1-(4-(3-Chloropropoxy)-2-hydroxyphenyl)ethan-1-one (CAS 172739-45-6)
- Methyl 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylate (CAS 1822439-70-2)
- N-(5-bromopyridin-2-yl)tetrahydrofuran-2-carboxamide (CAS 890995-40-1)
- tert-Butyl 3-((4,6-dimethylpyrimidin-2-yl)oxy)piperidine-1-carboxylate (CAS 1261230-37-8)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
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