2,4-Dichloro-5-(thiophen-2-yl)pyrimidine CAS 63558-74-7
| CAS No. | 63558-74-7 |
| Molecular Formula | C8H4Cl2N2S |
| Molecular Weight | 231.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dichloro-5-(thiophen-2-yl)pyrimidine (CAS 63558-74-7), molecular formula C8H4Cl2N2S and molecular weight 231.10 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 2,4-Dichloro-5-(thiophen-2-yl)pyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,4-Dichloro-5-(thiophen-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2N2S |
| Molecular Weight | 231.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,4-Dichloro-5-(thiophen-3-yl)pyrimidine (CAS 63558-75-8)
- 4,6-Dichloro-2-(thiophen-2-yl)pyrimidine (CAS 57059-13-9)
- 4,6-Dichloro-2-(thiophen-3-yl)pyrimidine (CAS 57059-14-0)
- 8,9-Dichloro-2,3,4,5-tetrahydro-1-benzoxepin-5-one (CAS 1094253-83-4)
- 4,6-Dichloro-3-isopropyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1211580-39-0)
- 4,6-dichloro-1-propyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1251465-05-0)
- 2-(4,6-Dichloro-2-cyclopropylpyrimidin-5-yl)acetaldehyde (CAS 1311275-29-2)
- 5,7-Dichloro-2-propyl-2H-pyrazolo[4,3-d]pyrimidine (CAS 1357087-31-0)
Recommended Standards
- 2,4,6-Tris(difluoromethyl)-1,3,5-triazine (CAS 369-22-2)
- 2-(4-Methylstyryl)-1,3,6,2-dioxazaborocane (CAS 608534-31-2)
- 2,6-Bis(trifluoromethyl)pyridin-4-ol (CAS 43150-55-6)
- 2-(2,3-Dihydro-1H-inden-2-yl)-1,3,6,2-dioxazaborocane (CAS 501014-44-4)
- 2-(4-Chlorophenyl)quinoline-4-carboxylic acid (CAS 5466-31-9)
- Methyl 3-(2,4-dimethylphenyl)-3-methyloxirane-2-carboxylate (CAS 1488148-95-3)
- 2,2,2-Trifluoro-1-(piperidin-3-yl)ethanone (CAS 1093759-81-9)
- 1-Methylpyrrolidine-3-carbothioamide (CAS 758662-77-0)
- 5-(1-Benzyl-5-chloro-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 400075-96-9)
- Methyl 2-amino-5-(pyrimidin-2-yloxy)benzoate (CAS 185154-82-9)
- SPDB (CAS 115088-06-7)
- 4-Cyclopropyl-3-fluoroaniline Hydrochloride (CAS 1255041-92-9)
- 3-((Butyl(methyl)amino)methyl)benzenethiol (CAS 1443348-42-2)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
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