Glutathione EP Impurity D CAS 636-58-8
| CAS No. | 636-58-8 |
| Molecular Formula | C8H14N2O5S |
| Molecular Weight | 250.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H14N2O5S, Glutathione EP Impurity D contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 250.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Glutathione EP Impurity D (CAS 636-58-8, C8H14N2O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14N2O5S |
| Molecular Weight | 250.27 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Glutathione Standards
- Glutathione Impurity 16 (CAS CATO-C4X-118516)
- Glutathione Impurity 18 (CAS CATO-C4X-118518)
- Glutathione Impurity 27 (CAS CATO-C4X-118527)
- Glutathione (CAS 1432061-73-6)
- Glutathione (1S, 2R)-Isomer (CAS 274260-05-8)
- Glutathione Reduced (CAS 70-18-8)
- Glutathione-(glycine- (CAS 815610-65-2)
- Glutathione EP Impurity A (CAS 19246-18-5)
Recommended Standards
- Rosuvastatin Impurity 107 (CAS 122549-26-2)
- Acetylcysteine impurity 69 (CAS CATO-C4X-153269)
- Atorvastatin impurity 163 (CAS 131000-98-1)
- Cefminox Impurity 15 (CAS CATO-C4X-192615)
- Desoximetasone Impurity 3 (CAS 59796-52-0)
- Leuprorelin EP Impurity H Trifluoroacetic acid (CAS 112710-58-4(free base))
- Vildagliptin Impurity 75 (CAS 1710765-32-4)
- Dequalinium Impurity 4 (CAS 16355-92-3)
- Lornoxicam Impurity 96 (CAS CATO-C4X-201696)
- 2-Ethylbut-3-en-1-ol (CAS 53045-70-8)
- Fluoromethane-d3 (gas) (CAS 558-21-4)
- 7-(3-(3-Cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl)heptanoic acid (CAS 75693-75-3)
- 1-CYCLOPROPYL-1H-PYRAZOL-5-AMINE (CAS 1501777-90-7)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
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