Nisoldipine CAS 63675-72-9
| CAS No. | 63675-72-9 |
| Molecular Formula | C20H24N2O6 |
| Molecular Weight | 388.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nisoldipine.
Nisoldipine (CAS 63675-72-9) is a high-purity analytical reference standard with the molecular formula C20H24N2O6 and a molecular weight of 388.41 g/mol.
The molecular framework of Nisoldipine (C20H24N2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Nisoldipine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O6 |
| Molecular Weight | 388.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Nisoldipine Standards
- Nisoldipine Impurity 3 (CAS CATO-C4X-18653)
- Nisoldipine USP Related Compound D (CAS 103026-83-1)
- (±)-Nisoldipine-d4 (2-nitrophenyl-d4) (CAS 1219795-47-7)
- Nisoldipine Impurity 4 (CAS 106685-70-5)
- Nisoldipine Impurity 4 (CAS 87375-91-5)
- Nisoldipine Impurity 1 (CAS 2226462-71-9)
- Nisoldipine Impurity 2 (CAS CATO-C4X-18652)
- Nisoldipine Impurity 6 (CAS 61312-59-2)
Recommended Standards
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- Allylestrenol Impurity 1 (CAS 3646-28-4)
- 4-(3,4-Dimethoxybenzamido)benzoic acid (CAS 887356-37-8)
- (S)-3-Amino-2-(4-bromo-phenyl)-propionic acid 1442114-45-5 KS-000025MJ (CAS 1442114-45-5)
- 1-PROPYL-1H-PYRROLO[2,3-C]PYRIDINE (CAS 1225586-53-7)
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- 2-(m-Tolyl)benzo[d]oxazole (CAS 14625-58-2)
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