1,4-Cyclohexanedione CAS 637-88-7
| CAS No. | 637-88-7 |
| Molecular Formula | C6H8O2 |
| Molecular Weight | 112.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,4-Cyclohexanedione is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1,4-Cyclohexanedione (CAS 637-88-7), molecular formula C6H8O2 and molecular weight 112.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,4-Cyclohexanedione (C6H8O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,4-Cyclohexanedione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8O2 |
| Molecular Weight | 112.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
Related Cyclohexanedione Standards
- 1,4-Cyclohexanedione-2,2,3,3,5,5,6,6-d8 1,4-Cyclohexanedione-d8 23034-25-5 (CAS 23034-25-5)
- 1,3-Cyclohexanedione (CAS 504-02-9)
- 1,2-Cyclohexanedione (CAS 765-87-7)
- 1,3-Cyclohexanedione-1,2,3- (CAS 1184998-71-7)
- 1,3-Cyclohexanedione-13C6 (CAS 1246820-51-8)
- 2-Methyl-1,3-cyclohexanedione (CAS 1193-55-1)
- 4056-73-9 2-Acetyl-1,3-cyclohexanedione DTXSID50193577 (CAS 4056-73-9)
- 1,4-Cyclohexanedione Monoethylene Acetal-d4 (CAS 56292-88-7)
Recommended Standards
- 3-Methyl-1,2-cyclopentanedione (CAS 765-70-8)
- 5-Methyl-2-furanmethanol (CAS 3857-25-8)
- 2-Hydroxy-3-methyl-2-cyclopentenone (CAS 80-71-7)
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- 2-Methyl-N-(thiophen-3-ylmethyl)propan-1-amine (CAS 892592-84-6)
- Populin (CAS 99-17-2)
- (1-Phenethyl-piperidin-4-yl)-acetic acid hydrochloride (CAS 1361116-72-4)
- 2-Bromo-N-(4-ethylphenyl)butanamide (CAS 1119450-18-8)
- Linagliptin impurity 167 (CAS CATO-C4X-1101167)
- Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride (CAS 1038866-44-2)
- 7-Iodoimidazo[4,3-b][1,3]thiazole (CAS 208722-53-6)
- Ethyl 1,7,7-trimethyl-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 1420792-70-6)
- N-(2-Hydroxyethyl)thiomorpholine (CAS 6007-64-3)
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