Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate CAS 6386-38-5

Purity >95%In StockPharmaceutical Standards
CAS No.6386-38-5
Molecular FormulaC18H28O3
Molecular Weight292.41 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate CAS 6386-38-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate.

Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate (CAS 6386-38-5), molecular formula C18H28O3 and molecular weight 292.41 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate (C18H28O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H28O3
Molecular Weight292.41 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at room temperature, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

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Why CATO?