Ibuprofen Impurity N18 CAS 126176-61-2
| CAS No. | 126176-61-2 |
| Molecular Formula | C18H28O3 |
| Molecular Weight | 292.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, a hydroxyl group, an ether linkage, Ibuprofen Impurity N18 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 292.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Ibuprofen Impurity N18 (CAS 126176-61-2, C18H28O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ibuprofen Impurity N18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H28O3 |
| Molecular Weight | 292.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
Related Ibuprofen Standards
- Ibuprofen Impurity 155 (CAS CATO-C4X-1082155)
- Ibuprofen EP Impurity R (CAS 102120-87-6)
- Ibuprofen Impurity 101 (CAS CATO-C4X-1082101)
- Ibuprofen Impurity 109 (CAS CATO-C4X-1082109)
- Ibuprofen Impurity 113 (CAS CATO-C4X-1082113)
- Ibuprofen Impurity 96 (CAS CATO-C4X-108296)
- Ibuprofen Piconol Impurity (CAS 64622-45-3)
- Ibuprofen Impurity 117 (CAS 127460-04-2)
Recommended Standards
- Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate (CAS 6386-38-5)
- n-Heptyltetraoxyethylene (CAS 28115-75-5)
- (S)-(+)-Dimethindene maleate (CAS 121367-05-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com