6-Amino-3-(2-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione CAS 639780-60-2
| CAS No. | 639780-60-2 |
| Molecular Formula | C11H10FN3O2 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Amino-3-(2-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 639780-60-2), a certified reference material (molecular formula C11H10FN3O2, MW 235.21 g/mol) for analytical method development and quality control.
Structurally, 6-Amino-3-(2-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (C11H10FN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 235.21 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Amino-3-(2-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10FN3O2 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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- Methyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-17-4)
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Recommended Standards
- 4-Methoxy-N-(propan-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 339011-19-7)
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- 4-Ethoxy-6-fluoroquinoline-2-carboxylic acid (CAS 301823-79-0)
- Ethyl 2-(3-fluorophenyl)oxazole-4-carboxylate (CAS 885272-98-0)
- 2,4-Difluoro-3-chlorobenzoic Acid (CAS 154257-75-7)
- 3-Bromo-1-(propan-2-yl)-1h-pyrazole (CAS 1354706-35-6)
- 3-[[(2-Chlorophenyl)methyl]thio]-1,2,4-thiadiazol-5-amine (CAS 447414-55-3)
- 1-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)butan-1-one (CAS 88795-86-2)
- 3-bromo-1-methyl-1H-indazol-7-amine (CAS 885271-76-1)
- 2-(2-Hydroxyphenyl)-3-(pyrimidin-2-yl)thiazolidin-4-one (CAS 821782-80-3)
- 3-(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)-1-(4-methylbenzenesulfonyl)urea (CAS 125069-22-9)
- 4-Bromo-3,5-dimethyl-1-(3-methylbutyl)-1H-pyrazole (CAS 1171717-09-1)
- N-(4-(cyanomethyl)phenyl)cyclobutanecarboxamide (CAS 949393-16-2)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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