7-(Dimethylamino)-2-(trifluoromethyl)quinazolin-4(1H)-one CAS 640297-59-2
| CAS No. | 640297-59-2 |
| Molecular Formula | C11H10F3N3O |
| Molecular Weight | 257.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
7-(Dimethylamino)-2-(trifluoromethyl)quinazolin-4(1H)-one (CAS 640297-59-2), molecular formula C11H10F3N3O and molecular weight 257.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-(Dimethylamino)-2-(trifluoromethyl)quinazolin-4(1H)-one (C11H10F3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F3N3O |
| Molecular Weight | 257.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethylamino Standards
- 2-(2-(Dimethylamino)pyrimidin-4-yl)-1H-purin-6(7H)-one (CAS 90185-52-7)
- 3-(Dimethylamino)-1-[3-(trifluoromethyl)phenyl]but-2-en-1-one (CAS 96604-34-1)
- 4-(Dimethylamino)-2-(4-fluorophenoxy)pyridine-3-carbonitrile (CAS 341967-05-3)
- 1-(2-(Dimethylamino)pyrimidin-5-yl)-3-phenylurea (CAS 1396861-25-8)
- 2-(3-((Dimethylamino)methyl)-4-hydroxy-5-methoxybenzylidene)malononitrile (CAS 860612-44-8)
- 4-(Dimethylamino)-2-(2-methoxyphenyl)pyrimidine-5-carbaldehyde (CAS 823796-61-8)
- Methyl 4-(dimethylamino)-2-phenylpyrimidine-5-carboxylate (CAS 823795-03-5)
- n-(4-(Dimethylamino)phenyl)-2-hydroxynicotinamide (CAS 923208-09-7)
Recommended Standards
- 5-{1-[3-(trifluoromethyl)phenoxy]ethyl}-1,2-oxazole (CAS 338976-13-9)
- Coumarin152 (CAS 53518-14-2)
- 5-(Furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 827588-61-4)
- ethyl 2-(butyrylamino)-3,3,3-trifluoro-2-hydroxypropanoate (CAS 328270-25-3)
- 951886-20-7 3-(5-(1,3-Dioxolan-2-yl)-2-thienyl)-1-propene MFCD09801342 (CAS 951886-20-7)
- 3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-61-0)
- N,N-Dimethylthiophene-3-sulfonamide (CAS 153439-45-3)
- 2-(3-Bromo-2-methylphenyl)acetonitrile (CAS 76574-42-0)
- Methyl cyclooctanecarboxylate (CAS 3724-54-7)
- Andropanolide (CAS 869807-57-8)
- 2-(2-Hydroxyethyl)-7-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 191096-41-0)
- 2-(Phenylsulfonyl)-3-(3-(trifluoromethyl)phenyl)prop-2-enenitrile (CAS 1025308-30-8)
- Ethyl 2-chloropyrimidine-4-carboxylate (CAS 1196152-00-7)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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