6-Nitrobenzofuran-2-carboxylic acid CAS 64209-68-3
| CAS No. | 64209-68-3 |
| Molecular Formula | C9H5NO5 |
| Molecular Weight | 207.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Nitrobenzofuran-2-carboxylic acid.
6-Nitrobenzofuran-2-carboxylic acid (CAS 64209-68-3), molecular formula C9H5NO5 and molecular weight 207.14 g/mol, is a CATO reference standard with documented purity and traceability.
6-Nitrobenzofuran-2-carboxylic acid (C9H5NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Nitrobenzofuran-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5NO5 |
| Molecular Weight | 207.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
Related Nitrobenzofuran Standards
- 4-Nitrobenzofuran-2-carboxylic acid (CAS 69604-06-4)
- 6-Nitrobenzofuran-5-carboxylic acid (CAS 342425-80-3)
- 5-Nitrobenzofuran-2-carboxamide (CAS 267644-49-5)
- 1-(4-Nitrobenzofuran-2-yl)ethanone (CAS 69603-98-1)
- 1-(5-Nitrobenzofuran-2-yl)ethan-1-one (CAS 23136-39-2)
- 2-Methyl-3-nitrobenzofuran (CAS 28439-73-8)
- (4-Nitrobenzofuran-2-yl)methanol (CAS 1935174-97-2)
- Methyl 5-nitrobenzofuran-2-carboxylate (CAS 104862-11-5)
Recommended Standards
- 6-Nitro-1H-indazole-4-carboxylic acid (CAS 885519-61-9)
- 6-Nitro-1,2-benzoxazole-3-carboxamide (CAS 35879-97-1)
- 6-Nitroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 904805-51-2)
- 6-Hydroxy-4,7-dioxo-4,7-dihydrobenzofuran-5-carboxamide (CAS 88258-47-3)
- Ethyl 1-benzyl-5,5-difluoro-4-hydroxypiperidine-3-carboxylate (CAS 1356339-08-6)
- 4-Bromo-6,7-dimethoxyquinoline-3-carboxylic acid (CAS 1378259-75-6)
- 3-(pyrazin-2-yl)propanoic acid (CAS 6705-34-6)
- Ethyl 6-amino-5-ethylnicotinate (CAS 1646681-18-6)
- Tepotinib impurity 16 (CAS CATO-C4X-337416)
- 3,7-dIethyl-3,6-nonadien-5-one (CAS 686778-04-1)
- 2-Methoxy-N-(2-methylbenzyl)benzamide (CAS 694518-20-2)
- Ethyl 5-iodopyrazine-2-carboxylate (CAS 1416575-48-8)
- 1-Bromo-4-((3-methylcyclobutyl)methoxy)benzene (CAS 1394024-01-1)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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