Tepotinib impurity 16 CAS CATO-C4X-337416
| CAS No. | CATO-C4X-337416 |
| Molecular Formula | C22H16BN5O3 |
| Molecular Weight | 409.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 409.21 g/mol gives Tepotinib impurity 16 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Tepotinib impurity 16 (CAS CATO-C4X-337416), a pharmacopoeial impurity reference standard (molecular formula C22H16BN5O3, MW 409.21 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tepotinib impurity 16 (C22H16BN5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tepotinib impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16BN5O3 |
| Molecular Weight | 409.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tepotinib Standards
- Tepotinib impurity 21 (CAS CATO-C4X-337421)
- Tepotinib impurity 23 (CAS CATO-C4X-337423)
- Tepotinib impurity 27 (CAS CATO-C4X-337427)
- Tepotinib Impurity N54 (CAS 1103506-79-1)
- Tepotinib impurity 20 (CAS CATO-C4X-337420)
- Tepotinib impurity 11 (CAS CATO-C4X-337411)
- Tepotinib impurity 14 (CAS CATO-C4X-337414)
- Tepotinib impurity 12 (CAS CATO-C4X-337412)
Recommended Standards
- N-(3,5-dichlorophenyl)-1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-42-8)
- (5-((4-Bromophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 318239-58-6)
- 5-Chloro-1-(4-chlorobenzyl)-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339024-72-5)
- 2-(4-Bromophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478068-09-6)
- Ilaprazole Impurity 83 (CAS CATO-C4X-113083)
- Pimavanserin impurity 58 (CAS CATO-C4X-193858)
- Amisulpride Impurity 64 (CAS CATO-C4X-104564)
- (3-OXO-3,4-DIHYDRO-2H-BENZO[B][1,4]THIAZIN-7-YL)BORONIC ACID PINACOL ESTER (CAS 2304634-93-1)
- Phenolphthalein complex indicator (CAS 25296-54-2)
- 2-Amino-4-nitrobenzenethiol (CAS 7686-29-5)
- O-Ethyl-L-homoserine (CAS 17268-93-8)
- p-Tolylhydrazine xhydrochloride (CAS 35467-65-3)
- 5-Amino-N-(2,4-dimethylphenyl)-1H-pyrazole-4-carboxamide (CAS 1187063-20-2)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
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