(2-(Trifluoromethoxy)phenyl)methanamine hydrochloride CAS 643087-98-3
| CAS No. | 643087-98-3 |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2-(Trifluoromethoxy)phenyl)methanamine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2-(Trifluoromethoxy)phenyl)methanamine hydrochloride (CAS 643087-98-3) is a high-purity analytical reference standard with the molecular formula C8H8F3NOHCl and a molecular weight of 227.61 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2-(Trifluoromethoxy)phenyl)methanamine hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8F3NO HCl |
| Molecular Weight | 227.61 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 3-Methyl-5-(trifluoromethoxy)benzaldehyde (CAS 1000339-55-8)
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- 3-(4-(Trifluoromethoxy)phenyl)propan-1-ol (CAS 1000519-40-3)
- 2-[4-(Trifluoromethoxy)phenyl]cyclopropan-1-amine (CAS 1001316-74-0)
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- 5-(Trifluoromethoxy)-2-(trifluoromethyl)-1H-indole (CAS 1007235-31-5)
- (4-(Trifluoromethoxy)benzyl)hydrazine 2,2,2-trifluoroacetate (CAS 1007599-47-4)
Recommended Standards
- 6-Bromo-2-(3-fluorophenyl)-4H-chromen-4-one (CAS 213894-73-6)
- 3,4-Dimethyl-5-nitropyridine (CAS 65169-36-0)
- 5-Bromo-N-butylpicolinamide (CAS 951885-14-6)
- (3-Fluoro-4-(4-methylpiperidine-1-carbonyl)phenyl)boronic acid (CAS 1449132-53-9)
- Elobixibat (CAS 439087-18-0)
- n-(2-Bromophenyl)-2-cyanoacetamide (CAS 80277-87-8)
- 1-Phenyl-1,4-diazepane acetate (CAS 1269393-99-8)
- TopFluor Cholesterol (CAS 878557-19-8)
- 2-(2-Methyl-1H-imidazol-1-yl)ethanol (CAS 1615-15-2)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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