Citalopram EP Impurity F oxalate CAS 64372-43-6
| CAS No. | 64372-43-6 |
| Molecular Formula | C19H21BrFNO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Citalopram EP Impurity F oxalate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Citalopram EP Impurity F oxalate (CAS 64372-43-6, C19H21BrFNOC2H2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Citalopram EP Impurity F oxalate (C19H21BrFNOC2H2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Citalopram EP Impurity F oxalate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21BrFNO C2H2O4 |
| Molecular Weight | 468.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Citalopram Standards
- Citalopram Impurity 38 (CAS 103146-26-5)
- Citalopram Impurity 17 (CAS 1187671-15-3)
- Citalopram EP Impurity D HBr (CAS 1188264-72-3)
- Citalopram-d6 N-Oxide (CAS 1189652-54-7)
- Citalopram-d6 (CAS 1190003-26-9)
- (R)-Citalopram-d6 N-Oxide (CAS 1217669-62-9)
- (S)-Citalopram-d6 N-Oxide (CAS 1217710-65-0)
- (S)-Citalopram-d6 Oxalate (CAS 1217733-09-9)
Recommended Standards
- Progesterone Impurity 64 (CAS 66875-13-6)
- Vildagliptin Impurity 27 (CAS 65732-69-6)
- Ozenoxacin Impurity 43 (CAS CATO-C4X-279643)
- 1-(5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-N-(3-(trifluoromethyl)phenyl)methanimine (CAS 648859-67-0)
- N-(3-Pyridinylmethyl)cyclohexanamine dihydrochloride (CAS 1158310-28-1)
- 2',4'-Dichloro-3-fluoro-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261893-02-0)
- 4-(2-Hydroxy-3-((2-methoxyphenyl)sulfonyl)propoxy)benzonitrile (CAS 478079-82-2)
- 2-(3,4-Dichlorophenyl)-2-oxoacetaldehyde (CAS 38923-36-3)
- 6-tert-butylpyridazin-3-amine (CAS 82560-18-7)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com