L-Histidine hydrochloride CAS 645-35-2
| CAS No. | 645-35-2 |
| Molecular Formula | C6H9N3O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
L-Histidine hydrochloride (CAS 645-35-2) is a high-purity analytical reference standard with the molecular formula C6H9N3O2HCl and a molecular weight of 191.62 g/mol.
Structurally, L-Histidine hydrochloride (C6H9N3O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 191.62 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2 HCl |
| Molecular Weight | 191.62 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related L Standards
- HISTIDINE Impurity 2 (CAS 1141479-01-7)
- DL-Histidine-α- (CAS 15474-90-5)
- D-Histidine Methyl Ester (CAS 17720-12-6)
- L-Histidine Methyl Ester Hydrochloride (CAS 18684-16-7)
- HISTIDINE Impurity 6 (CAS 1932060-69-9)
- L-Histidine-13C6,15N3 hydrochloride hydrate (CAS 202468-43-7)
- D-Histidine, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, compd. with cyclohexanamine (1:1) (CAS 210755-31-0)
- L-Histidine, 1-methyl-, methyl ester, hydrochloride (1:1) (CAS 256657-21-3)
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- 4-(5-Chlorothiophen-2-yl)oxazol-2-amine (CAS 1249507-76-3)
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- H-D-Glu-Obzl.HCl (CAS 78057-85-9)
- 2-Acetylbenzo[d]oxazole-5-carbaldehyde (CAS 1804501-95-8)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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