3-(5-(2-Nitro-4-(trifluoromethyl)phenyl)furan-2-yl)acrylic acid CAS 646497-91-8
| CAS No. | 646497-91-8 |
| Molecular Formula | C14H8F3NO5 |
| Molecular Weight | 327.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(5-(2-Nitro-4-(trifluoromethyl)phenyl)furan-2-yl)acrylic acid (CAS 646497-91-8), a certified reference material (molecular formula C14H8F3NO5, MW 327.21 g/mol) for analytical method development and quality control.
3-(5-(2-Nitro-4-(trifluoromethyl)phenyl)furan-2-yl)acrylic acid (C14H8F3NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(5-(2-Nitro-4-(trifluoromethyl)phenyl)furan-2-yl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F3NO5 |
| Molecular Weight | 327.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nitro Standards
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- Ethyl 2-Nitro-4,5-di(1-pyrazolyl)benzoate (CAS 1256633-25-6)
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Recommended Standards
- 2-Butyl-4-chloro-5-((4-chlorobenzyl)oxy)pyridazin-3(2H)-one (CAS 88094-23-9)
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- CAS 77369-58-5 (CAS 77369-58-5)
- alpha-(Trifluoromethyl)pyrimidine-5-methanol (CAS 1340063-42-4)
- 2-[2-(2-chlorobenzenesulfonamido)acetamido]acetic acid (CAS 1155505-13-7)
- 1-(5-Bromothiophen-2-yl)-3-ethoxyprop-2-en-1-one (CAS 1344886-67-4)
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- Neuropeptide AF (human) (CAS 192387-38-5)
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