3-Hydroxy-4-(2-nitro-4-(trifluoromethyl)phenoxy)benzaldehyde CAS 680185-90-4
| CAS No. | 680185-90-4 |
| Molecular Formula | C14H8F3NO5 |
| Molecular Weight | 327.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Hydroxy-4-(2-nitro-4-(trifluoromethyl)phenoxy)benzaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Hydroxy-4-(2-nitro-4-(trifluoromethyl)phenoxy)benzaldehyde (CAS 680185-90-4) is a high-purity analytical reference standard with the molecular formula C14H8F3NO5 and a molecular weight of 327.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Hydroxy-4-(2-nitro-4-(trifluoromethyl)phenoxy)benzaldehyde is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8F3NO5 |
| Molecular Weight | 327.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
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- Ethyl 6-hydroxy-1-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1160246-05-8)
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Recommended Standards
- 3-(Tert-butyl)-1-(2,4-dichlorobenzyl)-1H-pyrazole-5-carboxylic acid (CAS 306937-02-0)
- 4-Chloro-5-(1-(4-chlorophenyl)propoxy)-2-ethylpyridazin-3(2H)-one (CAS 88093-60-1)
- 3-(5-(2-Nitro-4-(trifluoromethyl)phenyl)furan-2-yl)acrylic acid (CAS 646497-91-8)
- 5-Amino-3-(tert-butyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-4-carboxamide (CAS 2380036-18-8)
- 3,5-Difluoro-4-methoxyaniline (CAS 363-47-3)
- 1-(4-Methoxy-2-methylphenyl)pyrrolidin-2-one (CAS 727993-66-0)
- 1,4-Bis((4H-1,2,4-triazol-4-yl)methyl)benzene (CAS 1286189-21-6)
- 1-Isopropyl-5-propyl-1h-1,2,3-triazol-4-amine (CAS 1510959-66-6)
- 2-bromo-4-methyl-3-nitro-pyridine (CAS 23056-45-3)
- Methyl 4-(aminomethyl)bicyclo[2.2.1]Heptane-1-carboxylate (CAS 916304-09-1)
- Allisartan Isoproxil Impurity 8 (CAS CATO-C4X-32178)
- 4-{2-[2,4-Di(tert-butyl)phenoxy]ethyl}piperidinehydrochloride (CAS 1219961-06-4)
- tert-Butyl ((5-methylpyrimidin-2-yl)methyl)carbamate (CAS 930272-56-3)
- [pGlu] Semaglutide (CAS CATO-C4X-2226288)
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