4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole CAS 64736-49-8

Purity 97%+In StockPharmaceutical Standards
CAS No.64736-49-8
Molecular FormulaC4HCl2F3N2
Molecular Weight204.97 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole CAS 64736-49-8 chemical structure

Description

The occurrence of 4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole (CAS 64736-49-8), molecular formula C4HCl2F3N2 and molecular weight 204.97 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, fluorine/chlorine substitution, 4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4,5-Dichloro-2-(trifluoromethyl)-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4HCl2F3N2
Molecular Weight204.97 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1975
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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