methyl 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxylate CAS 648410-22-4
| CAS No. | 648410-22-4 |
| Molecular Formula | C15H9Cl3FNO3S |
| Molecular Weight | 408.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.66 g/mol gives methyl 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
methyl 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxylate (CAS 648410-22-4), molecular formula C15H9Cl3FNO3S and molecular weight 408.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of methyl 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxylate (C15H9Cl3FNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures methyl 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9Cl3FNO3S |
| Molecular Weight | 408.66 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related methyl Standards
- N1-(4-fluorophenyl)-2-{[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]thio}acetamide (CAS 217490-35-2)
- 5-Ethyl-2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-1-phenyl-1H-pyrazol-3(2H)-one (CAS 104416-62-8)
- 1-(3-Fluorophenyl)-3-phenyl-1H-pyrazol-5-yl decanoate (CAS 922507-87-7)
- 3-{1-[2-(3-fluorophenyl)acetyl]piperidin-4-yl}-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775384-85-4)
- 1-Benzyl-3-(((2-fluorophenyl)amino)methylene)-1H-benzo[c][1,2]thiazin-4(3H)-one 2,2-dioxide (CAS 893313-83-2)
- 2,4-Bis(4-Fluorophenyl)-3,5-Diphenylfuran (CAS 18741-99-6)
- 2,5-Bis(4-Fluorophenyl)-3,4-Diphenylfuran (CAS 18749-93-4)
- N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (CAS 303997-97-9)
Recommended Standards
- 2,5-Bis(triethoxysilyl)thiophene (CAS 40190-22-5)
- N-((1-Decanoylpyrrolidin-2-yl)methyl)decanamide (CAS 61797-93-1)
- Stigmasterol Impurity 5 (CAS 119386-11-7)
- N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(3,4-dichlorobenzyl)acetamide (CAS 866157-73-5)
- 3-((5-Chloro-2-methylphenyl)sulfonyl)-2-isobutoxy-4,6-dimethylpyridine (CAS 338774-19-9)
- (2-Amino-5-methylthiazol-4-yl)methanol (CAS 859486-19-4)
- N-(4-((5-(N,N-Dimethylsulfamoyl)furan-2-yl)methoxy)phenyl)cyclopropanecarboxamide (CAS 1190252-41-5)
- 2,3-Dibromo-2-chloro-1,1,1,4,4,4-hexafluorobutane (CAS 63573-66-0)
- 2-Nitrobenzaldoxime (CAS 6635-41-2)
- 2-(Benzyloxy)-5-(2,2,2-trifluoroethyl)pyridine (CAS 1245646-58-5)
- 1-((4-(4-Fluorophenyl)tetrahydro-2H-pyran-4-yl)methyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 1251560-85-6)
- 7-Fluoro-1-oxoisoindoline-5-boronic Acid Pinacol Ester (CAS 957346-40-6)
- D-Praziquanamine (CAS 55375-92-3)
- 98035-79-1 Small cardioactive peptide A L-Methioninamide, L-alanyl-L-arginyl-L-prolylglycyl-L-tyrosyl-L-leucyl-L-alanyl-L-phenylalanyl-L-prolyl-L-arginyl- SCPA (CAS 98035-79-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com