N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide CAS 303997-97-9
| CAS No. | 303997-97-9 |
| Molecular Formula | C19H15F4N3OS |
| Molecular Weight | 409.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (CAS 303997-97-9), a certified reference material (molecular formula C19H15F4N3OS, MW 409.40 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (C19H15F4N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15F4N3OS |
| Molecular Weight | 409.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- (S)-5-(1-(1-(4-Fluorophenyl)ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolin-8-yl)benzo[d]oxazole (CAS 2123491-32-5)
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Recommended Standards
- 7-(((6-Methylpyridin-2-yl)amino)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol (CAS 308294-79-3)
- N-[3-(Morpholin-4-yl)propyl]-4-[3-(trifluoromethyl)benzoyl]-1H-pyrrole-2-carboxamide (CAS 439111-17-8)
- 5-Chloro-4-(((4-chlorophenyl)thio)methyl)-1-methyl-3-((p-tolylthio)methyl)-1H-pyrazole (CAS 318248-65-6)
- (inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 (CAS 307510-92-5)
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