5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-2-ylmethyl)-1H-indole CAS 651335-04-5
| CAS No. | 651335-04-5 |
| Molecular Formula | C20H20Cl2N2O2S |
| Molecular Weight | 423.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 423.36 g/mol gives 5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-2-ylmethyl)-1H-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-2-ylmethyl)-1H-indole (CAS 651335-04-5) is a high-purity analytical reference standard with the molecular formula C20H20Cl2N2O2S and a molecular weight of 423.36 g/mol.
Structurally, 5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-2-ylmethyl)-1H-indole (C20H20Cl2N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 423.36 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-2-ylmethyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20Cl2N2O2S |
| Molecular Weight | 423.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-3-((3-chlorophenyl)sulfonyl)-1-(piperidin-4-ylmethyl)-1H-indole (CAS 651334-84-8)
- (3E)-3-{[(2-chloro-4-fluorophenyl)methoxy]imino}-1-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]propan-1-one (CAS 339279-43-5)
- 3-[(4-Chloro-2-fluorophenyl)(oxo)methyl]-6-chloro-2-methyl-8-(morpholinomethyl)imidazo[1,2-b]pyridazine (CAS 1229236-83-2)
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(1Z)-{[(4-chlorophenyl)methoxy]amino}methylidene]thiourea (CAS 339114-06-6)
- 4-Chloro-N'-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethanimidoyl)benzohydrazide (CAS 306976-83-0)
- 2-Chloro-6-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)benzonitrile (CAS 339020-11-0)
- 2-Chloro-5-(2-(2-chloro-4-nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 25299-97-2)
- 3-Chloro-4-(2-(2-chloro-4-nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 25299-91-6)
Recommended Standards
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- Methyl 4-((1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluorobenzoate (CAS 208122-09-2)
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