1-(4,4-Difluoro-1-piperidinyl)-2,2,2-trifluoroethanone CAS 65220-85-1
| CAS No. | 65220-85-1 |
| Molecular Formula | C7H8F5NO |
| Molecular Weight | 217.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-(4,4-Difluoro-1-piperidinyl)-2,2,2-trifluoroethanone (C7H8F5NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 217.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(4,4-Difluoro-1-piperidinyl)-2,2,2-trifluoroethanone (CAS 65220-85-1) is a high-purity analytical reference standard with the molecular formula C7H8F5NO and a molecular weight of 217.14 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4,4-Difluoro-1-piperidinyl)-2,2,2-trifluoroethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8F5NO |
| Molecular Weight | 217.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
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- Methyl 4,5-Difluoro-2-nitrobenzoate (CAS 1015433-96-1)
- Methyl 3,5-difluoro-4-nitrobenzoate (CAS 1123172-87-1)
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Recommended Standards
- 1-(3-Trifluoromethylphenyl)-2-nitroethylene (CAS 62248-94-6)
- 1-(trifluoromethyl)-3-isocyanato-5-methoxybenzene (CAS 918525-00-5)
- 1-(2-Nitrovinyl)-4-(trifluoromethyl)benzene (CAS 99696-01-2)
- 1,3-Dihydro-5-(trifluoromethoxy)-2H-indol-2-one (CAS 403853-48-5)
- Ethyl 6-azaspiro[2.5]Octane-1-carboxylate (CAS 1088498-24-1)
- 4-((1H-Imidazol-2-yl)amino)benzene-1,2-diol (CAS 72467-78-8)
- (5-Chloro-6-(1H-imidazol-1-yl)pyridin-3-yl)boronic acid (CAS 2225155-01-9)
- S-(3-Aminopropyl) benzothioate hydrochloride (CAS 79417-77-9)
- 2-(4H-1,2,4-triazol-3-yl)piperidine hydrochloride (CAS 1820735-50-9)
- Ethyl 4-amino-4-methylpentanoate (CAS 1250519-23-3)
- 2,8-Dimethylimidazo[1,2-a]pyridin-3-amine (CAS 82193-27-9)
- 6-Isopropoxypyridazine-4-carboxylic acid (CAS 1437433-23-2)
- n1-Methyl-n1-propylbenzene-1,2-diamine (CAS 1094813-04-3)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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