1-(2-Chlorophenyl)-2,2-difluoroethan-1-one CAS 653-13-4
| CAS No. | 653-13-4 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2-Chlorophenyl)-2,2-difluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(2-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 653-13-4), a certified reference material (molecular formula C8H5ClF2O, MW 190.57 g/mol) for analytical method development and quality control.
1-(2-Chlorophenyl)-2,2-difluoroethan-1-one (C8H5ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 1-(3-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 1271473-74-5)
- 1-(4-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 655-54-9)
- 2-(3-Chlorophenyl)pyrazine (CAS 108030-82-6)
- 4-(4-Chlorophenyl)pyrimidine (CAS 458541-37-2)
- 5-(3-Chlorophenyl)pyrimidine (CAS 74963-05-6)
- 5-(4-Chlorophenyl)pyrimidine (CAS 82525-17-5)
- 4-Chlorophenyl methyl sulfone (CAS 98-57-7)
- 2-(4-chlorophenyl)propanoic acid 4-Chloro-alpha-methylphenylacetic acid 938-95-4 (CAS 938-95-4)
Recommended Standards
- 1-(2-chloro-3,6-difluorophenyl)ethan-1-one (CAS 890934-10-8)
- 1-(4-Chloro-2,5-difluorophenyl)ethan-1-one (CAS 655-12-9)
- (2-Chloropyrimidin-5-yl)dimethylphosphine oxide (CAS 2551118-33-1)
- (2,3-Difluorophenyl)acetyl chloride (CAS 808144-32-3)
- 5-Chloro-2-(difluoromethyl)-3-fluorophenol (CAS 2092102-01-5)
- 3-(2-Methoxybenzyl)pyrrolidine (CAS 191800-50-7)
- tert-Butyl 3-(((6-bromopyridin-2-yl)oxy)methyl)piperidine-1-carboxylate (CAS 1065484-40-3)
- 3,6-Dimethylpyrido[2,3-b]pyrazin-2(1H)-one (CAS 159104-70-8)
- Cyclopentyl 3,4,5-trifluorophenyl ketone (CAS 898792-02-4)
- (6-Chloroquinolin-3-yl)methanol (CAS 1307239-61-7)
- 6-Bromo-8-fluoro-1,2,3,4-tetrahydroquinoline (CAS 954267-76-6)
- (4-(1-Aminoethyl)phenyl)boronic acid (CAS 1258948-01-4)
- 4-Chloro-2-fluoro-5-(prop-2-yn-1-yloxy)aniline (CAS 84478-65-9)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
Why CATO?
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